Research Postdoctoral Fellow - Human Synaptic Physiology

Dr. Stewart Anderson has a postdoctoral fellowship in live imaging of synaptic activity using human stem cell-derived neurons available in his lab at the Children's Hospital of Philadelphia/University of Pennsylvania School of Medicine (https://www.research.chop.edu/anderson-laboratory). We are using human stem cell derived excitatory and inhibitory neurons, astrocytes, microglia, and neurovascular-like cells in mono-and mixed carpet cultures, as well as organoid differentiations, as tools for the study of gene-gene and gene-environment interactions in developmental neuropsychiatric disease. Illnesses of particular interest include schizophrenia and autism, with emphasis on mitochondrial influences on symptom penetrance.

This position requires experience in neuronal physiology, and preferably in live neuronal imaging, as well as a strong desire to learn about forebrain development in relation to neuropsychiatric disease in a highly collaborative environment. Cell culture experience, especially with mouse or human stem cells, is preferred. Additional experience in developmental neuroscience and basic molecular biology (i.e. basic RNA-seq informatics, RT-PCR, basic cloning, CRISPR-CAS or other gene editing) would be ideal.

Applicants should submit a CV, statement of research interests, and contact information of three references.