Director, Immuno-Oncology and Cell Therapy *PC 320

Are you ready to start revolutionizing biomedical research? When you join Miltenyi Biotec, you join a family that is passionate about making a real impact - one breakthrough at a time. For over 30 years, we have played a pivotal role in the design, development, manufacture, and integration of products for sample preparation, cell separation, cell analysis, imaging, and cell culture needs. These developments have led to cutting-edge cell and gene therapies - transformative methods that mobilize the body's own cells and genetic blueprint to tackle diseases such as cancer and autoimmune conditions. Today, our more than 18,000 solutions play a vital role in paving the way for the medicine of tomorrow.

Your Tasks:

As the Director of the Immuno-Oncology and Cell Therapy, you will have the exciting opportunity to lead a team of talented scientists and be responsible for overseeing the design, implementation, and execution of our research programs in immunology, with a particular focus on the development of cell-based therapies. In addition to R&D responsibilities, you will contribute to strategic discussions, develop internal and external collaboration and interact with other functions and departments. The role will have direct reports and sub-teams.

Essential Duties and Responsibilities:

• Oversee a dynamic team involved in the discovery and development of new CAR T products in the areas of hematologic and solid tumors, autoimmune disease and beyond.
• Develop new analytical approaches using Miltenyi's unique suite of spatial imaging, proteomic, and genomic instruments: MACSima, RNAsky, BlazeUltramicroscope.
• Implement innovative gene transduction methodologies such as engineered lentiviruses, novel virus-like particles, lipid nanoparticles, and electroporation using lab-scale and clinical-scale applications.
• Identify and facilitate implementation of new technologies, supervise the development of new projects, assays and platforms to address the emerging needs, and stay apace with the field.
• Furthermore, work collaboratively with the other groups and departments to advance translation of cell therapy projects with high quality documentation, presentation of data and reports.
• Take part in strategic discussion, goal setting exercise, stage-gate reviews.
• Facilitate advancement of projects through creating strong work relationships and connections between teams, mitigating obstacles and help shaping departmental strategies in the areas of cell therapy.
• Help head of R&D and key management leaders, and scientific affairs team in vetting clinical collaborators, provide scientific diligence, present preclinical data and advocate clinical transition. In some projects pre-clinical studies leading up to IND applications will be required.
• Help evaluating preclinical/clinical-stage licensing and collaboration and developing and evaluating the IP landscape in the field.

Requirements:

• Ph.D. in Immunology, Cell Biology or other related scientific discipline and extensive post-doctoral experience in related areas; 10+ years of experience with a proven track record of leading successful research programs in immunology, with a focus on the development of cell-based therapies; or a combination of education and experience.
• Proven track record of leading successful research programs in immunology, with a focus on the development of cell-based therapies for oncologic indications.
• Strong expertise in cellular immunology, including experience with CAR-T cell therapies and adoptive cell transfer approaches.
• Experience with preclinical and clinical development of immunotherapies, including IND-enabling studies and regulatory submissions.
• Excellent leadership and management skills, with the ability to motivate and mentor a team of scientists and researchers.
• Strong communication skills, with the ability to write scientific papers and reports and present research findings to internal and external audiences.
• Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these to support problem solving and delivery in a team-oriented, collaborative environment.

Preferred Qualifications:

• Experience working in a biotechnology or pharmaceutical company.
• Familiarity with regulatory requirements and guidelines for immunotherapy product development.
• Outstanding experience in translational research in advanced cell & gene therapies, including CAR T cell therapies.