2025 Summer Intern - System Engineer/Sequencing Development

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Department Summary

Roche Sequencing Solutions (Santa Clara) is a group at Roche developing nanopore based sequencing dedicated to making clinical genetic testing easy and affordable. We are developing a revolutionary, single-molecule DNA sequencer that will improve the lives of people in a wide variety of ways including timely screening for diseases and diagnosis of various cancers.

Roche is looking for a motivated and team-oriented individual who is passionate about revolutionary sequencing technology. The System Engineer Intern will become an expert on the operation, theory, and data analysis of the Roche Nanopore Sequencing platform. Following Roche product development processes, they will help take the instrument, microfluidic device and software from an advanced proof of concept to an operational laboratory system. Drawing on experience in engineering, computer science, biochemistry and/or materials science, the System Engineer Intern will design and implement experiments on the Roche sequencer and will help monitor, diagnose, improve, and analyze microfluidic devices, instrument and reagent interfaces, and processes. The candidate will analyze and present experimental and data exploration results around spatial and temporal variability and robustness of the microfluidic devices and the system, and work collaboratively across microfluidic sensor device, instrument, reagents, and system teams. The candidate must be self-motivated, details-oriented, and able to work well in a team.

This internship position is located in Santa Clara, on-site

The Opportunity

• Become an expert on the operation of the Roche Sequencing Platform

• Design, implement, and analyze single-molecule sequencing results of various microfluidic device process changes and various operating parameters

• Investigate, troubleshoot, and perform microfluidic sensor device development in a fast-paced environment

• Manipulate large data sets and apply data science, statistical methods, and/or process control monitoring techniques

• Excellent oral and written communication skills

Program Highlights

• Intensive 12-weeks, full-time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer)

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education - You meet one of the following criteria:

• Must be pursuing or have attained an Associate's Degree.

• Must be pursuing a Bachelor's Degree (enrolled student).

• Must have attained a Bachelor's Degree (not currently enrolled in a graduate program).

• Must be pursuing a Master's Degree (enrolled student).

• Must be pursuing a PhD (enrolled student).

Required Majors: engineering - biological, chemical, materials, mechanical; statistics, biochemistry, chemistry, or any related field.

Required Skills:

• The ability to perform statistical analysis of data with programs such as JMP, Matlab, R. and are familiar with computer programming in languages such as or Python OR

• Meticulous attention to detail and excellent written and electronic record keeping skills

• Excellent troubleshooting and problem solving skills, along with experimental design experience

• Strong oral and written communication skills

• Self-motivated and able to work well in a team

Preferred Knowledge, Skills, and Qualifications

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

• Prefer experience with statistical data analysis using JMP, python or

• Prefer understanding of or experience with microfluidics, sequencing methodologies, or other wet laboratory instrumentation

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $45.00-$50.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

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At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

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