Bioinformatics Research Scientist- Epigenetics Group

Job Responsibilities:

• Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check.
• Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis.
• Act as a liaison between end-users, software developers, system designers, and different departments.
• Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions.
• Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection.
• Develop programs to assist in the analysis of data within the databases.
• Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Minimum Education and/or Training:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
• Experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Qualifications:

Ideal candidates will have:

• Experience building, maintaining and optimizing analysis pipelines or installing tools for high-throughput next-generation sequencing data analysis (e.g., ChIP-Seq, ATAC-Seq, RNA-Seq, Hi-C, HiChIP, or Capture-C) in Linux/Unix environments.
• A solid understanding of basic epigenetic gene regulation mechanisms, like histone modifications, chromatin accessibility, DNA methylation or the 3D genome.
• Very good programming skills in Bash scripting language and Python (preferred) or R programming languages.
• Experience with version control systems such as Git.
• Strong communication and project managements skills.
• Experience with deep learning and Nextflow is a plus.

This is an exceptional opportunity to gain experience in diverse areas of bioinformatics, contribute to cutting-edge research, and play a vital role in advancing St. Jude's mission.

Responsibilities

• Specific responsibilities may include NGS data quality control, multi-omics integrative analyses, data visualization, and the development and evaluation of analytic tools. Excellent communication skills are essential. You will collaborate closely with various St. Jude Principal Investigators and their research teams to provide standardized or customized analyses, utilizing St. Jude's high-performance computing clusters and cloud computing environments.

Additional Requirements:

• Proficiency in programming (e.g., Python, R, C/C++, Perl, or other programming/scripting languages) in Linux/Unix environments is required.
• Proven ability to work effectively with a wide range of users.
• Demonstrated experience in analyzing and interpreting epigenetics data.
• Proven experience conducting independent data analyses and managing projects is required.
• Experience providing end-user support and training is required.

Compensation

Explore our exceptional benefits!

Diversity, Equity and Inclusion

St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.

Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

No Search Firms

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