Principal, Mission Ventures

The Cystic Fibrosis Foundation is a leading healthcare nonprofit organization like no other. For decades, we have been taking major steps and pioneering new ways to advance the mission to find a cure for cystic fibrosis and to provide all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, partnering with the CF community, and advancing high-quality, specialized care.

We are the global leader in the search for a cure for cystic fibrosis and nearly every CF drug and therapy available today was made possible because of CF Foundation support. We did this not only for the close to 40,000 people living in the U.S. with CF - and the estimated 105,000 people worldwide - but for the people with CF and families who have worked tirelessly to support the mission.

These achievements have required dedication and unwavering commitment from a talented team of CF Foundation employees. We promote an environment that attracts -- and retains -- a diverse group of talented people who are passionate about eradicating this disease . Join us and you will join an amazing team, devoted to our community, and our mission.

Position Description

The Cystic Fibrosis Foundation (CF Foundation) and its employees embrace their commitment to its core values. These core values are the pillars on which the CF Foundation stand and will continue to sustain us as we move forward.

• Keep sight of what really matters: Our decisions are based on what is best for people with cystic fibrosis and their families.

• Aspire for excellence in all we do: We take pride in our work. We are committed to continuous learning and improvement.

• Stronger together: We collaborate and work together so that we can learn more and achieve more.

• Innovate with courage: We embrace challenges. We reach beyond boundaries in pursuit of our vision.

• Care about our people: We deeply care about each other and all who support our shared mission. We listen with respect. We support one another.

We are a nonprofit, donor-supported organization that has raised and invested billions of dollars to help develop cystic fibrosis therapies that have changed the lives of people with this disease. Nearly every CF medicine available today was made possible because of Foundation support.

POSITION SUMMARY:

The Principal will support the development, management, and oversight of the Foundation's Mission Related Investments (MRI) portfolio. The Foundation has committed over $500M toward our genetic medicines-focused Path to a Cure (PTAC) and over $100M toward our Infection Research Initiative (IRI) by 2025. The Principal will have an exceptional opportunity to lead deals, support cutting-edge medicines, and interface with academic luminaries, entrepreneurs, and other investors. The Principal will play a pivotal role in expanding the Foundation's MRI strategy and execution.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Source new opportunities and investment partners in the biotechnology ecosystem including biotech companies, tech transfer offices, venture capital firms, and accelerators/incubators.

• Investment due diligence including evaluation of market differentiation, business plans, finances, management, board composition, etc.

• Support BD activities of portfolio companies by leveraging CFF and personal networks to ensure optimal syndicate composition.

• Preparing and presenting investment analysis and recommendations to our internal team and for larger investments, the Therapeutics Development Committee of the Board.

• Lead the negotiation and execution of investment agreements across an array of financial instruments including but not limited to SAFES, convertible notes, and equity.

• Develop strategic frameworks and sophisticated investment theses based on primary and secondary research on various therapeutic modalities.

• Post-investment monitoring through regular company updates, reports, and/or board roles.

• Improving the mission related investment process, including work on investment operations, performance management and risk management.

• Collaborate with cross-functional teams to inform, develop, and refine long-term financial planning models with a focus on capital allocation.

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

• Profound intellectual curiosity - a deep enthusiasm for:

  • Life science innovation and the evaluation of novel technologies.

  • Venture capital investing theory, process, and execution.

• 4 - 6 years of venture capital, search and evaluation, or business development or other relevant experience, including post-doctoral fellowships and advanced degrees in related disciplines.

• 6-10 years of relevant work experience, including graduate degree related research.

• A deal sheet demonstrating leadership roles in the closing of transactions required (please do not forget to submit when applying).

• Prior experience leading the sourcing and triage within a therapeutic modality including the development of competitive analyses using market maps.

• Prior experience creating sophisticated financial models for novel therapeutic platforms and product candidates; experience with long term strategic planning or capital allocation models is a plus.

• Working knowledge of core concepts in therapeutic development; experience in gene therapy and/or infectious disease is a plus.

• Preference for candidates with graduate degree (MS, PhD, or MD) in molecular biology or a related field and business education/training (MBA, consulting, buy-side business development, investment banking, or venture capital).

• Exceptional work ethic with a commitment to developing a wide range of skills and responsibilities.

• Ability to synthesize information from various sources and critically evaluate alternative approaches.

• Ability to prepare well-written, well-organized material and present recommendations in a clear and concise manner.

• High emotional intelligence with a strong ability to interface with a variety of internal and external stakeholders.

• Ability to collaborate and be creative with a professional and positive approach.

• Ability to take courageous, decisive action and make timely and independent decisions that are in the best interests of the Foundation.

REPORTING RELATIONSHIPS:

• Reports to Senior Director, Mission Related Investments. No direct reports.

WORKING CONDITIONS:

• Opportunity to work remotely or hybrid dependent on applicant location.

• No heavy lifting required.

• Travel up to 25% of time to attend investor, partnering, and scientific conferences and meetings, as necessary.

The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of essential functions, responsibilities or requirements.

This position will be posted for a minimum of 5 days or until the position is filled. Applications will be accepted on an ongoing basis, so candidates are encouraged to apply promptly if interested.

Total Rewards: The CF Foundation is committed to offering competitive compensation (base pay and incentive), benefits, and professional development opportunities that maximize our ability to recruit, retain, reward, and motivate a highly qualified and diverse workforce. Our comprehensive benefits package includes medical, dental, and vision coverage; a holistic well-being program; health savings and flexible spending accounts; employer-provided life and disability insurance; retirement savings benefits; and a variety of work-life benefits to support employees and their family members. In addition, the CF Foundation offers full-time employees 20 days of vacation and 10 days of sick per year, prorated based on hire date, as well as 14 paid holidays, 2 personal days, and a variety of generous leave benefits. Visit ourWhy Work at the Cystic Fibrosis Foundationpage to learn more.

The CF Foundation is an equal opportunity employer that is committed to being an employer of choice, not just a good place to work, but a great and inclusive place to work. We strive to recruit and maintain a diverse workforce. Qualified applicants will receive consideration for employment without regard to race, physical or mental disability, color, religious creed, ancestry, national origin, religion, age, sex, pregnancy, marital status, genetic information or testing, gender identity and expression, sexual orientation or status as a Vietnam-era or special disabled veteran or any characteristic protected by law.

Reasonable Accommodations: The CF Foundation is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or would like to request an accommodation due to a disability, please contact us at HROps@cff.org.