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Director, AI/ML Engineering

GlaxoSmithKline
United States, Pennsylvania, Philadelphia
5 Crescent Drive (Show on map)
Mar 31, 2025
Site Name: USA - Pennsylvania - Philadelphia, Durham Blackwell Street, Mississauga Milverton Drive, USA - Massachusetts - Waltham
Posted Date: Mar 31 2025

Join us to deploy and implement cutting-edge AI/ML models addressing complex challenges in life science R&D areas including target choice, patient identification, molecule design and clinical trial effectiveness. Collaborate with data scientists and leverage cloud infrastructure to build scalable training pipelines, ensuring rapid iterations and operational excellence. Develop robust backend systems and evaluation frameworks while engaging in technology assessments and co-development with strategic partners to support GenAI products across R&D functions.

Responsibilities:

  • Deploy and implement advanced AI/ML models to tackle complex problems in target choice, patient identification, molecule design/chemistry, manufacturing and controls (CMC), and clinical trial effectiveness.

  • Design and implement distributed training pipelines for LLMs using tools such as DeepSpeed, ensuring scalability and efficiency.

  • Collaborate with Data Scientists in LLM customization: pre-training, fine-tuning, reinforcement learning with human feedback (RLHF), and applying parameter efficient fine-tuning (PEFT) techniques.

  • Define and implement repeatable AI/ML pipelines to ensure rapid iterations of data science experiments while leveraging the cloud infrastructure to implement industry best practice in MLOps.

  • Model operationalization and monitoring on Azure and GCP infrastructures with close collaboration with the DevSecOps team.

  • Build scalable, reusable backend systems including the state-of-the-art agentic frameworks to support GenAI products across R&D functions. Develop robust logging, telemetry, and evaluation harnesses to ensure reliable model performance.

  • Technology assessment of external product solutions and co-development with strategic partners

  • Create and maintain pipelines for producing training/testing/validation data sets

  • Build and maintain model evaluation framework

Why You?

Basic Qualifications:

  • BS degree in computer science, engineering, bioinformatics or applied math

  • 5+ years of engineering experience

  • Experience working with LLM technologies, including GenAI embedding techniques, modern model architecture, retrieval-augmented generation (RAG), fine tuning/pre-training AI models, and evaluation benchmarks

  • Experience in Python, TensorFlow/PyTorch, and scalable ML architectures.

  • Experience in Agentic framework, i.e., AutoGen and LangGraph

  • Experience in Azure and GCP cloud services

  • Experience in full stack software development, and knowledge of software engineering principles around testing, code reviews and deployment.

Preferred Qualifications:

  • MA degree in computer science or engineering

  • 10+ years of combined full stack, data engineering, Azure/GCP cloud services, and AI engineering experience

  • Experience with graph databases in the context of GraphRAG

  • Experience with data lake-house architecture, data catalog, master data management applications

  • Experience in establishing AI/ML and agent best practices, standards, and ethics

  • Experience in AI/ML applications in life science domain areas: pre-clinical research, clinical trial design and operation, precision medicine, regulatory science, and CMC.

  • Experience in reducing the cost of running a service / capability while maintaining or improving performance efficiencies

  • Strong analytical and problem-solving skills, with a passion for shaping AI-driven workflow.

  • Strong written and verbal communication skills

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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