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Postdoctoral Trainee

University of North Carolina - Chapel Hill
Dependent upon experience and qualifications
United States, North Carolina, Chapel Hill
104 Airport Dr (Show on map)
Apr 17, 2025
Posting Information
Posting Details


Department Marsico Lung Inst - CF Center - 426401
Posting Open Date 04/16/2025
Application Deadline 04/21/2025
Open Until Filled No
Position Type Postdoctoral Scholar
Position Title Postdoctoral Trainee
Vacancy ID PDS004505
Full-time/Part-time Full-Time Temporary
Hours per week 40
FTE 1
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range Dependent upon experience and qualifications
Proposed Start Date 08/01/2025
Estimated Duration of Appointment 12 Months
Position Information


Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.
Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.
UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.
Primary Purpose of Organizational Unit
The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.

The goal of the Marsico Lung Institute and the Cystic Fibrosis/Pulmonary Research and Treatment Center is to provide the mechanism for generating world-class research into the pathogenesis and treatment of diseases that impact on the human lung. Basic research activities focus on the elucidation of the pathogenesis of human lung diseases at the molecular, biologic, cell biologic and physiologic levels. Clinical and therapeutic studies focus on specific disease categories, exploring pathophysiologic concepts in patients with these diseases, and, with the collaboration of basic and clinical investigators, developing rational, novel ways for treatment of lung diseases.
Position Summary
This Postdoctoral Trainee position is available through a NIH T32 training program, designed to train promising early career investigators. The postdoctoral trainee will focus on the pathogenesis of host pulmonary responses to injuries, including infectious agents. A central area of interest will be on host responses to injury that produce airways ectasia, e.g., bronchiectasis and/or bronchiolectasis. Topics of interest in this context would include: 1) the role of obstruction and luminal/epithelial hypoxia in pro-inflammatory/pro-ectatic airway responses; 2) the roles of anaerobic bacteria in the pathogenesis of ectasia; and 3) genes that both initiate and modify ectatic lung diseases. The studies will utilize high-content spatial transcriptomics and proteomics technologies, aerobic/anaerobic cell culture technologies, single-cell RNAseq technologies, Qpath/Visiopharm/site-based image analyses, murine studies, histology, qPCR, and interface with explanted human lungs for translational studies.

Essential duties of the Postdoctoral Trainee include:
* Designing and carrying out studies;
* Analyzing and interpreting data;
* Publishing papers describing these results, all with the mentor.

Career development of the Postdoctoral Trainee will be an important component of this position.
Minimum Education and Experience Requirements
A PhD in Infectious Disease, Immunology, Pathology, Genetics, Cell and Molecular Physiology, or similar discipline required and/or MD.
Required Qualifications, Competencies, and Experience
Experience in Infectious Disease, Immunology, Pathology, Genetics, Cell and Molecular Physiology, or similar discipline required.
Preferred Qualifications, Competencies, and Experience
Preferred qualifications include:
1) Coursework or knowledge in infectious disease, immunology (particularly inflammation and innate immunity), cell and molecular physiology, and/or pathology of disease,
2) Experience and proficiency in some of the technologies described above, in particular imaging analyses
3) Experience in mouse models of lung disease.
Special Physical/Mental Requirements
N/A
Special Instructions
For information on UNC Postdoctoral Benefits and Services click here
Quick Link https://unc.peopleadmin.com/postings/300044
Posting Contact Information


Department Contact Name and Title Stephanie Fleming, HR Consultant
Department Contact Telephone or Email stephanie_fleming@med.unc.edu
Postdoctoral Affairs Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the University's Office of Postdoctoral Affairs at (919) 962-9982 or send an email to opahr@unc.edu.

Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.

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