Research Associate Scientist I

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A Brief Overview
This role is an independent researcher that plans, coordinates and executes research projects.

Works with the principal, investigator. Participates in and assists in the planning and coordination of research projects. Is independent and responsible for a specific aspect of one or more research project. Assists in determining the direction of the project.

About the Laboratory

Dr. Lindsey George's laboratory studies the molecular basis of coagulation and how disturbances in their function lead to disorders of bleeding and thrombosis. We are interested in translating basic molecular and biochemical insights to improve therapeutics for disorders of hemostasis, namely hemophilia. Specifically, we are interested in developing novel gene addition or gene editing approaches for hemophilia and understanding the mechanism of inhibitor formation in hemophilia.

A variety of enzymatic, biochemical, and molecular biology techniques are used in the laboratory in order to carry out our specific goals. For example, the following techniques are routinely performed in the laboratory: modern molecular methods (site-directed mutagenesis, cloning, etc.), tissue culture, protein purification, HPLC, FPLC, SDS-PAGE, ELISA, enzymatic kinetic assays, fluorescence spectroscopy, fluorescence anisotropy measurements, mouse modeling of hemostasis, designing AAV vectors etc. We aim to expand our gene editing work. Experience with gene editing technology, iPSC, and advanced molecular biology techniques is preferred.

What you will do

• Assists faculty in the conduct of research of significant value in the basic and/or translational science area
• Plans, conducts research projects within the federal, institutional regulations and policies
• Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
• Trains technical staff, students in lab procedures
• Reviews manuscripts for peer-reviewed journals
• Assists with the submission of grant applications, contracts and research projects funding
• Participates in free discussion, research progress, and overall morale
• Responsible for appropriate use of research funds
• May supervise students or other research staff as assigned

Education Qualifications

• Bachelor's Degree - Required
• Master's Degree - Preferred
• Doctorate - Preferred

Experience Qualifications

• At least seven (7) years of directly relevant post grad scientific lab experience - Required
• At least nine (9) years of directly relevant post grad scientific lab experience - Preferred
• Successful completion of a Post Doc Fellowship - Preferred

Skills and Abilities

• Expert knowledge in the use of a wide variety of lab techniques, research equipment and research related software
• Excellent verbal and written communications skills
• Excellent organizational skills
• Excellent critical thinking / problem-solving skills
• Excellent analytical skills
• Solid interpersonal skills
• Basic leadership skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, professionals working onsite-at any CHOP location, for any portion of time-must be vaccinated for COVID-19. Learn more.

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