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Research Technician, Fly Lab - Malik Lab

Howard Hughes Medical Institute (HHMI)
United States, Washington, Seattle
April 30, 2022
Primary Work Address: 1100 Fairview Avenue North, Seattle, WA, 98109

Current HHMI Employees, click here to apply via your Workday account.

We are seeking a Research Technician to support the lab of Dr. Harmit Malik in the Basic Sciences Division at the Fred Hutch Cancer Center site in Seattle, WA. Harmit Malik studies conflicts that occur in our genomes as different genetic entities try to maximize their evolutionary success. Malik and his team are interested in understanding the mechanisms and consequences of these "molecular arms races" and how they drive recurrent genetic innovation, from the perspective of both evolutionary biology and human disease. The team usesDrosophilaas a model organism to study centromeres, which are crucial for chromosomal stability during cell division; mobile genetic elements, which can impact host fitness and genome organization; and proteins that evolve rapidly due to their involvement in host-parasite interactions. More information on the lab can be found on their

We seek candidates interested in microbiology with experience with molecular biology techniques. This position is ideally suited for candidates who seek research experience before going to graduate school or other opportunities.

What You'll Do:

This position will help carry out an exciting research project focusing on genetic conflicts under the mentorship of the PI and a senior member of the lab. The work will involve routine handling of fruit flies, bacterial cultures, extensive molecular biology (e.g. molecular cloning, nucleic acid extractions, sequencing, qPCR, western analysis), and presentation and organizational tasks.

  • Secondary responsibilities include lab support activities (e.g. maintaining media stocks), ordering scientific lab supplies, and maintaining equipment.

  • Based on the interest and ability of the technician, they may also be solely responsible for the development and execution of independent, small-scale research projects. Successful projects in which the candidate participates may lead to authorship on scientific publications.

  • Handling biosafety level 2 organisms, molecular biology, and routine bioinformatics will be required.

Skills You Bring:

  • Bachelor's degree in Biology or a related discipline - or equivalent education and experience

  • Specific experience with DNA extraction, PCR, gel electrophoresis, molecular cloning, transformation, aseptic technique, and handling bacterial cultures is required.

  • Ability to participate in lab meetings and presentation of data

  • Experience working with microscopy, tissue culture or fruit fly genetics and husbandry (or other model organisms) is highly preferred, but not essential.

  • Participation in lab meetings and presentation of data will be required.

  • Excellent communication skills are a must. Superior verbal and written communication and routine computer skills (PC/Mac)

  • Must work well in a team of scientists working at the interface of evolutionary, molecular, and microbiology.

  • Must be independent and motivated to think, plan, and conduct experiments

  • Meticulous attention to detail is essential.

  • Ability to apply experience to new techniques and protocols and learn complex tasks with general instruction.

  • Superior organizational skills in recordkeeping, multitasking, prioritizing responsibilities, time management, and an ability to interact with all levels of staff are requirements.

Preferred Qualifications

  • Biochemistry experience is highly preferred but not essential.

  • Genetics experience highly preferred, but not essential.

  • Experience working with microbiology, evolutionary biology, and bioinformatics is highly preferred but not essential.

Finalists are asked to submit a statement of their commitment and contributions to diversity, equity, and inclusion they have made in their career and/or will make toward greater diversity and antiracism through their work at Howard Hughes Medical Institute.

To apply, in addition to your resume, please include a 1-page cover letter including the following information: - Why are you interested in this position? -What do you want to learn from this job? - Why do you think you would be a good candidate for the position? - What are potential start dates that would work for you? - What are your long and short-term career goals (including your ideal time frame for the next stages in your career)?

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

HHMI is an Equal Opportunity Employer
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