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Postdoctoral Associate - Espinosa-Medina Lab

Howard Hughes Medical Institute (HHMI)
United States, Maryland, Chevy Chase
4000 Jones Bridge Road (Show on map)
May 08, 2023
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Summary:

The Espinosa-Medina Lab at HHMI Janelia is looking for a Postdoctoral Associate to study how the nervous system and the cells of the organs, specifically the pancreas, interact during development and in disease states. We will use innovative imaging technologies and new genetic tools for temporal manipulation of cells in vivo (in zebrafish and mouse), to define the cellular origins and interactions underlying the development of the neuroendocrine system, which regulates lifelong glucose homeostasis. Moreover, the findings will guide engineering of more physiological in vitro 3D systems in which to better model health and disease conditions. In the long-term, we plan to extend these studies to other organs (e.g., liver, lungs) to determine multiorgan interconnections in vivo. As members of the new 4DCP area at Janelia, we envision to participate in a broad collaborative strategy to determine general principles of cell and tissue organization across systems.

We believe that science is for everyone. We hire researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.

In the Espinosa-Medina lab, you will learn pioneering labelling and imaging techniques to visualize cells in whole embryos or tissues within their native context. You will also learn new genetic manipulation techniques and how to apply them to various model systems. The Espinosa-Medina will work collaboratively with Cell Map (FIB-SEM technology), computational biologists, experts in molecular tools and microscopy which will allow lab members to experience an interdisciplinary research environment and develop strong collaborations. By joining Janelia as a postdoctoral associate, you will have access to career development workshops and mentoring groups. This will help you strengthen your skills (e.g. communication, writing, time management, leadership, etc) as you prepare the next step in your career.

Learn more about the Espinosa-Medina lab work

Please include a cover letter, resume, and 2-3 contact references with your application.

Essential Duties and Responsibilities:
  • Use novel imaging and genetic tools to assess neuronal - endocrine cell interactions in vivo (fixed mouse samples or live zebrafish larvae).

  • Explore and analyze resulting data with data science techniques.

  • Participate in collaborative projects with imaging tool builders and computational researchers.

Qualifications:

Education:

  • Ph.D. degree in biology, neurosciences, developmental biology, molecular biology, genetics, genomics, or related disciplines.

Skills and Abilities:

  • Experience in molecular biology, histology and imaging techniques.

  • Previous experience handling a model organism (mouse or zebrafish is a plus).

  • Optional: experience with genomic assays (e.g. scRNASeq), FACS/flow cytometry and computational skills are a plus, but not required.

  • Effective communication in English (speaking, writing) required.

  • Ability to work both collaboratively and independently.

  • Ability to communicate your research with the community and the public.

  • Most importantly, we are looking for candidates who are passionate about science, creative, and willing to work in a highly collaboratively and interdisciplinary environment!

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

Compensation:

An Associate 00 is compensated at a rate of $74,200.00 annually at HHMI's Janelia Research Campus.

HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

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