Postdoctoral Research Associate - Oncology

Project Description:

The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of pre-leukemic conditions including clonal hematopoiesis of indeterminate potential (CHIP) and myelodysplastic syndrome (MDS). Our ultimate goal is to identify and validate novel treatments that selectively target malignant clones and prevent their transformation into myeloid leukemias.

Position Responsibilities:

In this position, you will gain extensive experience and training in genomics, stem cell biology, computational biology, in vivo models of disease, and pre-clinical study development. You will have the opportunity to develop and lead projects using several cutting-edge model systems including:

• Isogenic immortalized cell lines generated using CRISPR-Cas genome editing
• Novel xenograft and transgenic in vivo model systems
• Induced pluripotent stem cells
• Primary patient samples

Minimum Education and/or Training:

Successful applicants will have a Ph.D. in molecular biology, cell biology, genetics, computational biology or a related field; a strong publication record; and excellent communication skills.

Special Skills, Knowledge, and Abilities:

To succeed in this position, applicants must have a strong cell and molecular biology background and an interest in working with in vivo model systems. Applicants with expertise in hematopoietic stem cell biology, genome editing, RNA biology, immunology, or computational biology are strongly encouraged to apply.

About the lab and St. Jude:

The Obeng lab is a highly collaborative and interactive environment focused on the scientific development of trainees. Our lab supports and encourages diversity and promotes career development including grant writing; participation in relevant, immersive courses or workshops; and presenting work from the lab at national and international meetings.

Located in the heart of Memphis, Tennessee; a vibrant city at the historic American crossroads of music, commerce, food and culture; St. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. We are the first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Over 300 principal investigators and their research teams work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment with the shared goal of improving the diagnosis and treatment of children with catastrophic diseases.

We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have:

• A Blend of Academic Freedom and Industrial Efficiency: You will have access to over 20 lab-based institutional shared resources and facilities led by expert scientists and equipped with cutting-edge equipment.

• Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness. This includes access to grant writing workshops, teaching and mentoring opportunities, a generous professional development allowance, and much more.

• Competitive Compensation: Embark on your journey with a competitive salary starting at $70,000 a year, comprehensive benefits and generous relocation assistance.
• A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced training experience.

Diversity, Equity and Inclusion

St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.

Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

No Search Firms

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