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Lead OR Principal Bioinformatics Research Scientist

St. Jude Children's Research Hospital
United States, Tennessee, Memphis
262 Danny Thomas Place (Show on map)
Sep 24, 2024
When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a "Best Place to Work."

Why St. Jude?

St. Jude isn't just a hospital; it's a beacon of hope and innovation in the world of biomedical research. Here, the brightest minds come together to decode the mysteries of human diseases like cancer. Our research center is a leader in mass spectrometry-based proteomics, metabolomics, and multi-omics data integration, driving technologies that are redefining what's possible in science and medicine. Explore more about our lab in the Center for Proteomics and Metabolomics here.

What's in It for You?

  • Innovate with Impact:Engage with large, complex datasets that are the foundation for groundbreaking tools and technologies. Your work will play a crucial role in advancing our understanding of disease mechanisms and discovering new therapeutic interventions.

  • Lead and Grow:Take the helm of collaborative projects and lead your own cutting-edge scientific research. This role offers you the chance to develop your leadership skills, advance your career, and contribute to high-impact publications that shape the future of biomedical research.

  • Cutting-Edge Environment:Join a creative, dynamic research environment where your ideas are valued, and your contributions have the potential to change the course of science and medicine.

Position Overview:

As a Principal/Lead Bioinformatics Research Scientist at St. Jude, you will be at the forefront of research efforts that integrate multi-omics data to understand complex biological systems. Our projects focus on both small-scale and large-scale Omics data, with a particular emphasis on proteomics and metabolomics, which are the core of our group's work. We are eager to expand our efforts by merging proteomics and metabolomics with existing genomics data.

Our research group engages in collaborative projects that span both basic research and clinical applications, with a 70/30 split respectively. We anticipate a shift toward more clinical data over the next 2-5 years. Additionally, we are deeply involved in the development of new bioinformatics tools for proteomics, metabolomics, and integrative Omics data, with the goal of impacting both treatment options and diagnostic approaches.

Lead Bioinformatics Research Scientist

Minimum Education:

  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:

  • Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience.
  • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Responsibilities:

  • Lead data analysis and deliver high-quality results by formulating advanced and/or new analytical approaches with the available data/ to address challenging data analysis questions.
  • Deliver data files, and document the analytical process. Participate in manuscript preparation at project's conclusion.
  • Establish and document protocols or best practices for common research tasks.
  • Recommend ideas to automate or improve existing analysis methods and implement the improvement.
  • Evaluate and test new methods and technologies. Develop reusable code and pipeline. Participate in redistribution and education of novel methods to research community when required.
  • Lead and participate in the department's developmental projects and interdepartmental team projects. Act as a project manager when required.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.

    A reasonable estimate of the current salary range is $125,840 - $238,160 a year for the role of Lead Bioinformatics Research Scientist.

    Principal Bioinformatics Research Scientist

    Minimum Education :

    • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
    • Master's degree or PhD preferred.

    Minimum Experience:

    • Bachelor's degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
    • Experience Exception: Master's degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience.
    • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred.

    Responsibilities:

    • Design and lead advanced analyses and deliver high-quality results in a timely manner by identifying new technologies and methodologies and recommend for adoption when appropriate.
    • Coordinate development of novel software tools and infrastructure as a scientific and technical advisor, by contributing code and providing scientific guidance to developers.
    • Conceptualize, initiate, and lead manuscript preparation and submission of benchmarking results, new pipelines, databases, and scientific discoveries where appropriate.
    • Establish best practices and new protocols for analysis matching skills and expertise, and share protocols with St. Jude investigators through open documentation and hands-on training.
    • Assist in acquiring funding to support methods evaluation, development, and infrastructure.
    • Lead and coordinate the development of curriculum to educate the St. Jude community.
    • Is an independent project leader for large-scale projects and mentors junior staff.
    • Perform other duties as assigned to meet the goals and objectives of the department and institution.

    Compensation

    In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Lead OR Principal Bioinformatics Research Scientist.

    Explore our exceptional benefits!

    Diversity, Equity and Inclusion

    St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.

    Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

    St. Jude is an Equal Opportunity Employer

    No Search Firms

    St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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