Research Post-Doc Fellow - Cardiovascular and Metabolic Biology and Disease -Dr. Pei Lab
Children's Hospital of Philadelphia | |
retirement plan | |
United States, Pennsylvania, Philadelphia | |
Aug 29, 2024 | |
SHIFT: Day (United States of America)A Brief Overview Assume responsibility for an on-going, innovative research project as a Postdoctoral Fellow at CHOP. Our postdoc experience will broaden your skillset, scientific background, and research capabilities. About the Laboratory A postdoctoral fellow position is available in the laboratory of Dr. Liming Pei at the Center for Mitochondrial and Epigenomic Medicine, and Cardiovascular Research Institute at the Children's Hospital of Philadelphia (CHOP) and University of Pennsylvania (UPenn). Our laboratory uses a range of molecular and cellular biology, mouse genetics, and single-cell multiomics technologies to study cardiovascular and metabolic biology and disease. The candidate will work closely with the other members of the research team. Our recent publications include: Zhao, J., and Pei, L (2020). Cardiac Endocrinology: Heart-Derived Hormones in Physiology and Disease. JACC Basic Transl Sci 5, 949-960. PMID: 33015416. PMCID: PMC7524786. Pei L, Wallace DC (2018). Mitochondrial Etiology of Neuropsychiatric Disorders. Biological Psychiatry 83, 722-730. PMID: 29290371. PMCID: PMC5891364. Zhao J, Lupino K, Wilkins BJ, Qiu C, Liu J, Omura Y, Allred AL, McDonald C, Susztak K, Barish GD, Pei L. (2018) Genomic integration of ERR-HNF1 regulates renal bioenergetics and prevents chronic kidney disease. Proceedings of National Academy of Sciences 115, E4910-E4919. PMID: 29735694. PMCID: PMC6003475. Li J, Liu J, Lupino K, Liu X, Zhang L, Pei L. (2018) GDF15 maturation requires proteolytic cleavage by PCSK3, 5 and 6. Molecular and Cellular Biology. 38 (21). pii: e00249-18. PMID: 30104250. PMCID: PMC6189459. Wang T, Liu J, McDonald, C, Lupino K, Zhai X, Wilkins BJ, Hakonarson H, Pei L (2017). GDF15 is a heart-derived hormone that regulates body growth. EMBO Molecular Medicine 9, 1150-1164. Wang T, McDonald C, Petrenko NB, Leblanc M, Giguere V, Evans RM, Patel VV, Pei L (2015). ERRalpha and ERRgamma are essential coordinators of cardiac metabolism and function. Molecular and Cellular Biology 35, 1281-1298. Pei L*, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM* (2015). Dependence of hippocampal function on ERR regulated mitochondrial metabolism. Cell Metabolism 21, 628-636 (* co-corresponding author, featured in cover). Faculty page: http://www.med.upenn.edu/apps/faculty/index.php/g275/p8651729 https://www.ncbi.nlm.nih.gov/myncbi/liming.pei.1/bibliography/public/ CHOP's Commitment to Diversity, Equity, and Inclusion Responsibilities * Participate in project planning, recording, and evaluation of data. * Conduct independent scholarly research, developing new methods and protocols under the guidance of a mentor (principal investigator). * Acquire technical, lab management, and grant writing skills. * Participate in seminars, lectures, poster sessions, national presentations, and professional workshops. * Supervise junior lab members. * Assist with other research projects as needed. Education Qualifications
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