Pathology Senior Research Associate

Job Description

General Summary:

Preclinical Safety Assessment (PSA) is a global function responsible for the design and conduct of comprehensive nonclinical safety programs. Its pathology team supports animal model development and efficacy at all stages of discovery for the evaluation of candidate therapeutic agents. We are seeking a Senior Research Associate to perform histology techniques, data acquisition and compilation using state-of-the-art molecular pathology techniques to join our (PSA) team at Vertex. The incumbent will interface closely with other scientists, veterinary pathologists and histotechnologists in PSA as well as other cross-functional project teams to provide timely, high-quality data to support multiple projects across our drug development pipeline.

Key Duties and Responsibilities

• Conduct routine histology techniques including tissue processing, trimming of tissues of diverse origin, embedding, paraffin block microtomy and cryo-sectioning
• Setup and perform routine pathology staining techniques including H&E, IHC and special stains using manual and automated platforms (Ventana and Leica)
• Perform routine whole-slide brightfield and fluorescent scanning for morphometric. analysis
• Maintenance of laboratory equipment
• Generates detailed and accurate laboratory (ELN) records, follows good laboratory and GLP-like practices and ensures proper archiving of pathology specimens
• Work closely with board-certified anatomic pathologists to review, QC, and share results with stakeholders

Knowledge and Skills:

• Excellent histology skills including tissue trimming, embedding, staining, scanning and digital pathology platforms is preferred
• Ability to multi-task, prioritize and provide timely, high-quality results on multiple projects simultaneously in a fast-paced environment
• Excellent written and oral communication skills are required

Education and Experience:

• Bachelor's or Master's Degree in Biological Sciences or equivalent combination of education and experience
• Bachelor's (or equivalent) and 4+ years experience in a research or pharmaceutical-based histology laboratory
• Master's Degree (or equivalent) and 0-2 years experience in a research or pharmaceutical-based histology laboratory
• ASCP certification (HT or HTL) a plus
• Prior clinical or industry experience in histology a strong plus

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Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com