Post Doctoral Fellow - Department of Cancer Biology - Lab of Dr. Christine Eischen

The Eischen laboratory needs a highly motivated postdoctoral fellow. Postdoctoral fellows should be interested in genetic, molecular, or biochemical mechanisms of tumor development and survival. The laboratory utilizes genetically engineered mouse models, primary cell culture, retroviral gene transfer technologies, protein purification, genomics, microscopy, computational biology, and patient sample analysis, to answer biological questions related to tumor initiation and survival. We published in high profile journals (e.g., Nature Comm. 2017 and 2020, J. Clinical Invest. 2017, Clinical Can. Res., 2017, Cancer Res. 2019, and Leukemia 2020).

Project 1 focuses on BCL2 family members and their roles in B cell lymphoma survival and drug resistance. This project involves biochemical, cellular, and mouse modeling approaches to characterize various BCL2 family members and ways to capitalize on their targeting for the treatment of lymphomas and overcoming resistance to treatments.

Project 2 is focused on non-coding RNA in carcinomas (lung, breast, etc.) and lymphomas and their contribution to its development, growth, and progression. Mouse models, cellular, computational biology, and various other approaches to evaluate non-coding RNA and their targets are utilized.

PhD or M.D. required. Applicants must be skilled in cancer biology techniques (e.g., biochemistry, cell culture, mouse models, flow cytometry, etc.).

Jefferson Health delivers state of the art healthcare services to patients throughout the Delaware Valley and southern New Jersey. Jefferson (Philadelphia University + Thomas Jefferson University) provides more than 8,400 students from nearly 40 states and 40 countries with 21st century professional education. Combined, we have over 30,000 employees.

Jefferson Health, with 14 hospitals (seven are Magnet designated by the ANCC for nursing excellence) and 40+ outpatient and urgent care locations, offers a broad range of primary and complex, highly specialized care that touches the lives of more than four million patients annually. U.S. News amp; World Report has ranked Thomas Jefferson University Hospital among the nationrsquo;s best in eight specialties. Jefferson Health also includes the NCI designated Sidney Kimmel Cancer Center; it is one of only 70 such centers in the nation.

Thomas Jefferson University has ten colleges and three schools that offer more than 160 undergraduate and graduate programs. Our University is dedicated to inter-professional and transdisciplinary approaches to learning that offer a vibrant and expandable platform for professional education. Through this unique model, we are preparing our students for current and yet to be imagined careers.

As an employer, Jeffersonmaintains a commitment to provide equal access to employment. Jefferson values diversity and encourages applications from women, members of minority groups, LGBTQ individuals, disabled individuals, and veterans.