Position Details
Position Information
| Recruitment/Posting Title |
Postdoctoral Associate in Structural Virology |
| Department |
Proteomics |
| Salary |
Commensurate With Experience |
| Posting Summary |
The Kaelber lab is recruiting a scientist to work on the boundaries of structural biology and virology, using cryo-electron microscopy to answer fundamental questions in viral gene delivery and infection of mammalian cells, and to contribute toward structure-based rational design of viral nanotechnologies such as gene therapy vectors. This position will involve significant collaborations with scientists in academia and industry. Training will be provided in cutting-edge cryogenic ultramicroscopy technologies including cryoFIB. Mentorship of 1-2 undergraduate students will be encouraged. The proposed experimental portfolio is balanced with both low-risk and high-risk experiments.
BSL-2 pathogens will be utilized. Areas of specific focus include adeno-associated virus and other mammalian parvoviruses.
The candidate will culture and infect cells with recombinant virions and leverage
in situ nanoimaging techniques to understand the molecular mechanisms of nuclear entry and uncoating.
The Kaelber lab is located in the Institute for Quantitative Biomedicine, home to several experts in cryoEM and in molecular dynamics. The building is shared with the
RCSB Protein Data Bank (
PDB). Prof. Kaelber also directs the Rutgers New Jersey Cryo-electron Microscopy & Tomography Core Facility, which contains four electron microscopes including North America's first "Aquilos 2"-model cryogenic focused ion beam/scanning electron microscope as well as a Krios cryoTEM. |
| Position Status |
Full Time |
| Posting Number |
24FA0858 |
| Posting Open Date |
09/03/2024 |
| Posting Close Date |
|
Qualifications
| Minimum Education and Experience |
Terminal degree in life sciences or chemical sciences. Exceptional candidates with 5+ years' relevant research experience may also be considered at the Research Assistant level. |
| Certifications/Licenses |
|
| Required Knowledge, Skills, and Abilities |
At least one of the following is required, but more are preferred:
* Excellence in classical and molecular virology
* Excellence in biochemistry
* Excellence in cryoelectron tomography
* Excellence in structural bioinformatics
Additionally required skills are:
* Commitment to ethical conduct of research
* Self-motivation and independence
* Good documentation habits
* Proficiency with Unix command line
* A track record of productive, "wet-lab" results |
| Equipment Utilized |
Cryo-transmission electron microscope; cryo-focused ion beam; cryo-scanning electron microscope; cryo-fluorescence microscope; biosafety cabinet; ultracentrifuge; plate reader; vitrification robot |
| Physical Demands and Work Environment |
Experiments require fine manual dexterity for manipulation of small objects under cryogenic conditions, and vision in low light conditions. |
| Overview |
|
| Statement |
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Posting Details
| Special Instructions to Applicants |
Applicants should provide a cover letter relating their research and career interests to this position, a full curriculum vitae, and names and contact information for three references. Applications will be reviewed on a rolling basis until the position is filled. Must be willing to start by 1 December 2024. |
| Quick Link to Posting |
https://jobs.rutgers.edu/postings/234919 |
| Campus |
Rutgers University-New Brunswick |
| Home Location Campus |
Busch (RU-New Brunswick) |
| City |
Piscataway |
| State |
NJ |
| Location Details |
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Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings. Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination. Affirmative Action/Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement |
Rutgers University
Sep 03, 2024