Technical Research Assistant I BWH Neurology Shen Lab

The Shen Lab, a molecular neurobiology laboratory at Brigham and Women's Hospital and Harvard Medical School, seeks a Technical Research Assistant (TRA) to participate in exciting research on elucidating mechanisms of Alzheimer's and Parkinson's diseases using genetic approaches. This is an opportunity for someone looking to work in a rigorous academic research setting on projects that may lead to novel therapeutic treatments for these neurodegenerative diseases. This position is ideal for recent college graduates looking to expand their knowledge and experience before pursuing a graduate program. Opportunities for hands on experiments include PCR, RT-PCR, Western blotting, Northern blotting, cell culture, histology, microscopy, mouse and fly brain dissection, stereotaxic injection, mouse behavioral testing, and mouse colony maintenance. Our research assistants are encouraged to participate in all scientific aspects of the lab and are provided training and mentorship to help them achieve their career goals. Previous candidates for this position have had the opportunity to conduct their own research experiments and contribute to ongoing research projects in a meaningful way, resulting in co-authorship on published papers.

The TRA should be able to work collaboratively and independently after initial training period, and will follow hospital and departmental policies and procedures. Compensation will be generous and based on experiences and qualifications.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

• Independently performs routine experiments, which may include PCR, RT-PCR, Western blotting, mouse brain immunohistology, stereotaxic viral injection, and mouse behavioral testing of learning and memory or motor coordination.
• Maintain a variety of genetic mutant mice, including breeding and genotyping.
• Participate in data presentation and scientific journal manuscript preparation.
• Prepares laboratory reagents, instruments, and equipment for research scientists.
• Maintains records of experiments performed.
• All other duties as assigned.

QUALIFICATIONS:

• BS in a biological/physical science required.
• Prior coursework in genetics and molecular biology preferred.
• Experience working with mice desired.
• Candidates should have 1-2 years of experience in a research setting, such as performing PCR, Western blotting and/or immunohistochemistry.

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

• Must have excellent organizational and record keeping skills.
• Must possess careful attention to detail.
• High degree of computer literacy.
• Requires good oral and written communication skills.

WORKING CONDITIONS:
TRA will be working in a normal laboratory environment. TRA will be working with Drosophila (fly) or mice, and may be exposed to a variety of chemicals. Light lifting and bending required, as well as some computer/desk work.

BWH is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.