Postdoctoral Research Fellow - Molecular Cardiology Research Institute Jaffe Lab

The Molecular Cardiology Research Institute at Tufts Medical Center in Boston, invites post-doctoral applications for a position to study hormonal regulation of vascular function and disease in the laboratory of Dr. Iris Jaffe. Clinical studies support that an excess of the hormone aldosterone promotes vascular remodeling and atherosclerosis and that inhibition of aldosterone interaction with the Mineralocorticoid Receptor (MR) decreases mortality, heart attacks, and strokes. The Jaffe lab is investigating the molecular mechanisms by which MR regulates vascular function in order to identify new therapeutic targets to prevent or treat cardiovascular diseases in humans.

A highly motivated Postdoctoral Research Fellow is sought, ideally with prior experience in molecular biology and/or in animal physiology. The laboratory uses state of the art molecular and cellular biology assays, large scale genomics and proteomics, ex vivo vascular function studies, and state-of-the-art mouse models of vascular injury and atherosclerosis to address clinically relevant questions in vascular biology and physiology. The successful applicant will work closely with the Principal Investigator on research projects studying the vascular mechanisms contributing to hypertension, vascular dysfunction and cardiovascular disease. As needed, the individual will be required to independently develop protocols and establish new methodologies in the laboratory. The applicant would be intimately involved in writing and presenting new discoveries. The position requires:

Minimum Qualifications:

1. MD, PHD or both in a relevant field of study

Preferred Qualifications:

1.Prior experience in molecular biology and/or in animal physiology is desirable.

2. Excellent Verbal and Written Communication

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Duties and Responsibilities: The duties and responsibilities listed below are intended to describe the general nature of work and are not intended to be an all-inclusive list. Other duties and responsibilities may be assigned.

1. Conducts independent research projects within the healthcare field, under the guidance and mentorship of senior researchers.

2. Designs and implements research studies, including experimental protocols, data collection methods, and statistical analysis plans.

3. Analyzes and interprets research data, using appropriate statistical techniques and software.

4. Prepares research findings for publication in peer-reviewed journals and present at conferences and scientific meetings.

5. Collaborates with other researchers and professionals to develop and refine research hypotheses, study designs, and methodologies.

6. Stays updated with the latest advancements and breakthroughs in healthcare research and apply relevant knowledge to ongoing projects.

7. Assists in securing research funding by contributing to grant writing and research proposal development.

8. Collaborates with healthcare professionals and institutions to collect clinical data and samples for research purposes.

9. Contributes to the development and validation of new diagnostic tools, treatments, and interventions.

10. Participates in the preparation of research reports, progress updates, and grant applications.

11. Mentors and provide guidance to undergraduate and graduate students involved in research projects.

12. Collaborates with industry partners to translate research findings into practical applications and technologies.

13. Collaborates with regulatory bodies and ethics committees to ensure compliance with research protocols and regulations.

14. Contributes to the dissemination of research findings to healthcare professionals, policymakers, and the general public through various channels, such as seminars, workshops, and publications.

15. Maintains accurate and organized records of research data, protocols, and results, ensuring data integrity and confidentiality.