Scientist, mRNA Formulation

GlaxoSmithKline
United States, Massachusetts, Cambridge
Nov 21, 2024
A career in Boston - main video - YouTube At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we've invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life. Are you seeking an opportunity where you can lead through influence using your technical expertise and contribute to the development of potential new vaccines? If so, this Scientist role could be an exciting opportunity to explore! As a Scientist, you will lead the design and execution of scientific studies for vaccine technical programs as they progress from early development into Phase 1, 2, Phase 3, technology transfer and process performance qualification at the intended commercial site. Using your advanced background, you will work alongside high performing scientists to drive vaccine product understanding of novel vaccines. Key Responsibilities: Independently lead planning, design, execution, and interpret results of specific development projects appropriate to clinical development phases and following the Quality by Design framework. Contribute and drive mRNA delivery solutions and product understanding of RNA and protein-based vaccines. Contribute to design, execute and interpret results for improved mRNA delivery systems, and to the advanced analytical characterization. Interpret results, prepare and communicate conclusions and recommendations for next steps to relevant members. Make sound scientific/technical and business decisions based on a balance of data, analysis and experience. Author technical sections of internal and external reports with minimal supervision. Prepare and present scientific data within Technical R&D (TRD) including Technical Development Team and may represent GSK externally (conferences, etc.) Utilize innovative mindset to provide cutting edge solutions for technical challenges that yield tangible value to the organization and patients. Utilize scientific knowledge and experience to influence technical decisions. Function effectively as a core team member on multiple concurrent projects and lead small projects Generate strong relationships in the area of technical development with high quality partners beneficial to the organization, both internally and externally, to strengthen development/implementation of new methods/technologies. The successful applicant may spend 3-6 months within the first year of hire in Rockville, MD to support and guarantee a smooth transition of methods and know-how to the new laboratories in Cambridge, MA. Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: PhD degree in Bio/Chemical Engineering, Pharmaceutical Sciences, Bio/Chemistry, or related scientific field or MSc with 4+ years of industry experience or BSc with +6 years of industry experience. One or more years of experience in mRNA and/or vaccine formulations. Preferred Qualifications: If you have the following characteristics, it would be a plus: Good understanding of biopharm/vaccine development process. In-depth knowledge and hands on experience with mRNA delivery and liposome/nanoparticle formulations and/or protein formulation Experience with high-throughput screening and/or analytical characterization techniques (UV-Vis, fluorescence, SLS/DLS, particle characterization, FTIR, IR, DSC, chromatography, etc). Ability to deal with complexity, strong problem-solving and self-directional abilities. Demonstrated ability to independently lead, design, conduct, and analyze experiments. Experience mentoring/leading junior scientists in experimental design, data analysis, data presentation, etc. Strong organizational skills and the ability to manage multiple priorities in a matrix environment. Excellent written and verbal communication skills. Demonstrated ability to build strong internal and external relationships that drive product understanding. #VX-Cam #LI-GSK Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.