Vertex Spring 2025 Co-op, Gene Editing & Delivery (Boston, MA)

Job Description

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops,and feel valued by the Vertex community. Not only will co-ops learn about their day-to-day tasks through their specific work assignments, but they will interact and have exposure to our organizational leaders and their teams.

Job Summary:

Vertex Pharmaceuticals is seeking a 6-month Co-op to join the gene editing and delivery team. This position will contribute to our research efforts in non-viral delivery and gene editing to treat life-threatening diseases. The candidate will work with team members to test and optimize candidate molecules for tissue/organ-specific targeting. The ideal candidate is expected to have experience in protein chemistry, lipid nanoparticles (LNPs) and in vitro assays to analyze cellular uptake of candidate molecules.

Key Responsibilities:

• Test and optimize antibody conjugation methods for efficient protein labeling with small molecules and macromolecules.
• Design assays to quantify protein internalization and uptake of LNPs in different cell types.
• Maintain cell culture regularly to support in vitro assay development.
• Screen and nominate new candidate molecules for tissue/organ-specific targeting.
• Document study designs and experiment procedures using the electronic lab notebook.
• Work in a cross-functional manner to learn new skills and disseminate acquired skills for effective teamwork and collaboration.
• Present high-quality data to the team and department.

Qualifications:

• Ph.D. degree (degree obtained or currently pursuing) in cellular biology, biochemistry, biophysics, biomedical engineering or related disciplines.
• Master's degree (degree obtained or currently pursuing) in cellular biology, biochemistry, biophysics, biomedical engineering or related discipline
• Hands on experience in cell culture, protein chemistry (e.g. conjugation, purification and internalization etc.), bioanalytical methods (e.g. qPCR, Western blot, immunocytochemistry etc.).
• Permanent legal authorization to work in the United States
• Candidate must be enrolled in an advanced degree program if graduating before May 2025
• Candidate must be available to work full-time, 40 hours per week from January - June 2025

Program Dates: January - June 2025, Full Time

This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer.

Company Information