Senior Bioinformatics Research Scientist

The Center for Applied Bioinformatics at St. Jude Children's Research Hospital is looking for a highly motivated and creative senior bioinformatics scientist to develop and apply innovative analytical approaches to establish the molecular classifier of pediatric cancers. The scientist will have the opportunity to explore newly available methods, pipeline development could result in high profile publications, as long as it aligns with our ultimate goal: "Finding cures. Saving children".

The Centerprovides a highly interactive environment with collaborative opportunities within the center including transcriptomics group, genomics group, and genetics group, and across basic and clinical departments, access to high-performance computing clusters, cloud computing environment, novel sequencing platforms such as long reads sequencing technologies, single-cell sequencing at both DNA and RNA level and spatial transcriptomics, innovative visualization tools, highly automated analytical pipelines powered by GPU technology and mentorship from scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The members of this center could work on broad areas of bioinformatics and gain valuable experience. The members ofthis Centeralso have the opportunity to publish high-profile papers with prominent authorship and file patents for novel biomarker discoveries or novel methods for clinical diagnosis or disease treatment.

The successful candidate is expected to have strong programming skills in Bash, Python, and R, strong machine learning skills for classification, and experience in developing computational methods and optimizing analysis workflows for high-throughput next-generation sequence data (such as transcriptome sequencing, whole-genome sequencing and so on) under the Linux/Unix environment.

Responsibilities

• Specific responsibilities involve the build and refinement of the approach and machine learning models for classification/subtyping of pediatric cancers.
• Other responsibilities may involve NGS data quality control, integrative analyses, data visualization, developing and evaluating analytic tools.
• Excellent communication skills are essential.

Minimum Requirements

• PhD degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.

Job Responsibilities:

• Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
• Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
• Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
• Assist in the evaluation and testing of new methods and technologies.
• Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
• Participate in the department's developmental projects and interdepartmental team projects.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Minimum Education and/or Training:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
• Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation

Explore our exceptional benefits!

Diversity, Equity and Inclusion

St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.

Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.