Senior Research Scientist

About Certara

Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries.

In the past 6 years, over 90% of companies that received new drug approvals by the FDA used our software or services. Together with our partners, we use biosimulation and technology-enabled services to transform drug discovery and development across all therapeutic areas and innovative therapies.

We have an immediate opening for a Senior Scientist with experience in the pharmaceutics / biopharmaceutics area to work primarily on oral absorption physiologically based pharmacokinetic (PBPK) modelling (less or more qualified candidates may be considered at different levels).

Responsibilities

The successful candidate will join a team of around 7 scientists involved in researching, developing, specifying, and testing of new software features (algorithms, tools) related to simulating drug product absorption and bioavailability within the Simcyp (Biopharmaceutics ) Simulator. For this post there is strong emphasis on developing and disseminating case studies demonstrating the performance of the modelling tools. Experience in pharmacokinetics, drug product bioequivalence analysis, and hands-on use of PBPK software are all advantageous but not essential.

In addition, the post holder is eventually expected to provide on-going customer support, education, and training related to the use of the Simcyp PBPK Simulator, including to act as tutor at Simcyp workshops. The post does not include laboratory or clinical work. We offer a unique and exciting mix of academic and commercial environments which encourage regular attendance at scientific meetings as part of continuous education programs and publication in peer reviewed journals. The projects are scientifically challenging yet focused on solving practical issues relevant to modern drug development and hence collaborative work with pharmaceutical companies is part of the activities. All scientists are expected to participate in writing scientific reports relevant to their work under the guidance of our world-leading senior scientists within the group.

Qualifications

• PhD (or equivalent experience) in Pharmaceutics or a related area with transferable skills.
• Working knowledge and understanding of the mechanisms governing oral drug absorption, drug product delivery and the impact of critical quality attributes on product performance coupled with a willingness to expand knowledge in these areas.
• Demonstrable communication skills, as evidenced by presentation at scientific meetings, peer reviewed publications, and good interpersonal and organizational skills.

Desirable

• Practical knowledge of in vitro experiments used to assess drug product release/dissolution.
• Working knowledge of PBPK models
• Use of PBPK modelling in industrial settings and regulatory interactions
• Awareness of R&D processes in pharmaceutical companies

Certara bases all employment-related decision on merit, taking into consideration qualifications, skills, achievement, and performance. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.