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Senior Director, Medical Affairs - CF (Hybrid)

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Sep 16, 2025

Job Description

General Summary:

The Medical Affairs Senior Director provides medical and scientific leadership in Cystic Fibrosis (CF). This role will work closely with a cross-functional group to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs and will ensure the flawless execution of CF US medical plans.

Key Duties and Responsibilities:

  • Critically interprets scientific data and determines the potential impact of new research on scientific and medical understanding of assigned products

  • Shares country/regional insights with global teams to ensure global medical strategies and activities reflect the needs of the country/region; share insights with cross-functional partners as appropriate

  • Provides fair and balanced medical information and education to health care professionals and payers that support the safe and effective use of Vertex drugs in the appropriate patients

  • Fosters patient access to Vertex drugs, by supporting the commercial organization in the preparation/review of reimbursement dossiers and presenting scientific data as required to key stake holders in the access process

  • Performs/oversees medical/scientific training for field medical teams, commercial, and other internal stakeholders

  • Contributes to cross-functional teams and US Medical teams, representing the TA (scientific and medical expertise) and ensuring all activities address patient well-being and respect data integrity

  • Ensures compliance at country level with company policies, medical affairs SOPs, GCP and ICH

  • Assesses local promotional materials and ensures that all claims are fully supported by scientific data, and are presented in an accurate, fair and balanced manner

Knowledge and Skills:

  • Strong understanding of statistical methods

  • Experience in writing or reviewing scientific communications

  • Good understanding of the pharmaceutical business

  • Ability to develop relationships in a highly matrixed environment, as well as external relationships with leaders and industry experts

  • Experience in designing, planning and executing medical education and communication activities

  • Ability to engage in positive dialogue and resolve conflicts in a constructive manner

Education and Experience:

  • Terminal scientific degree (e.g., PhD or PharmD)

  • Requires 10+ years of experience or the equivalent combination of education and experience

Pay Range:

$240,000 - $360,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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