Scientist (Mass Spectrometry)

At Quest Diagnostics, our Scientists will be responsible for supporting the development, validation and transfer of both FDA and non-FDA analytical methods for the quantification of various analytes (i.e. small molecules) by GC-MS, LC-MS/MS.This professional will plan, prepare, conduct and record complex bench level chemical/biochemical experiments, reports and analysis of results. Activities may be focused on individual projects or assignments as a member of a project team which may include project leadership duties.

This person will work within the R&D Mass Spectrometry group developing clinical mass spec- based assays for diagnostics testing.

• Plans, conducts, performs and executes laboratory experiments for GC-MS, LC-MS/MS for both defined and novel protocols. Reports status of assigned projects by preparing detailed reports and documentation that critically interprets and summarizes results from complex experiments within a specific project or technology area.
• Effectively utilizes and applies advanced methods by maintaining knowledge of technological developments that may assist in the completion of an assignment or lead to novel ideas by reading current literature and attending scientific meetings and training.
• The individual will be expected to generate, compile, analyze and evaluate analytical data for technical reports including regulatory submissions, SOPs, validation reports. The candidate will be encouraged to submit abstracts for posters/presentations at scientific meetings.
• Identifies problems, investigates alternatives and recommends possible courses of action.
• Able to troubleshoot and resolve technical difficulties
• Ability to perform and prioritize multiple tasks/projects
• Other responsibilities include working with infectious materials, supporting and complying with the company hazard waste handling practices.

Qualifications:

The ideal candidate will have experience or strong understanding of various laboratory techniques including, but not limited to: sample preparation & extraction (i.e. precipitation, solid phase extraction) analyte quantitation using isotopically-labeled internal standards, or familiarity with HPLC and mass spectrometry. Prior experience in enzymology/enzyme assay development, compound optimization, operation and troubleshooting of various GC-MS, LC-MS/MS platforms is a plus.

A successful candidate will be a self-starter capable of performing experimental work. This professional will have a strong foundation in technical skills and has the ability to work independently and in collaboration with other team members - should be familiar with common data processing software (Excel, R, etc.) and should be able to present data in a meaningful manner.

Education:

• BS with 2-3 years of related experience
• MS with 1 year of related experience
• PhD and one year Post Doc experience, or related.
• Experience working in a biochemical genetics and chemistry laboratory setting is preferred.