Senior Principal Software Engineer
 Broad Institute | |
paid time off, paid holidays, 401(k), retirement plan
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 United States, Massachusetts, Burlington | |
 Oct 15, 2025 | |
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Description & Requirements The Broad Institute, Genomics Platform is seeking a Senior Principal Software Engineer to help lead our Data Analysis & Operations team. This position will be instrumental in the development of our high scale cloud-based orchestration platform for running genomics pipelines and performing data delivery. An ideal candidate will help design, build, and maintain the necessary infrastructure, as well as, coordinate and lead the technical activities needed to support exciting new projects on the platform, for both internal and external stakeholders. This is a fast-paced role that sits in the intersection of engineering, science, and business. A successful candidate will need to work effectively across multiple departments, partners, and with a wide community of computational biologists and medical/cancer geneticists. We're looking for a team player that thrives on opportunity, adjusts well to change, and has the passion to make themselves, their teammates, and our partners better. Here at Broad our collaborators are large-scale institutions (government, industry, academic, and philanthropic) that partner with us to generate clinical and genomic data, build new algorithms, and make it all available to researchers through our open-source analysis platform. We routinely partner with organizations across the biomedical ecosystem as well as scientists in our local MIT, Harvard, and affiliated hospital neighborhood. Everything that goes on at the Broad, almost without exception, involves the use of specialized software. Software engineers create our advanced algorithms, deliver solid infrastructure, and high quality portals. Software engineers at the Broad Institute are highly valued and classified as Staff Scientists.
SKILLS / TECHNICAL KNOWLEDGE / CERTIFICATION REQUIREMENTS:
The Broad Institute will not offer visa sponsorship for this opportunity. The expected base salary range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.
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