Analytical Development Senior Research Associate

Job Description

Vertex is seeking a talented scientist to join our Analytical Development group in Boston, MA.This individual will help advance transformative medicines treating the underlying cause of serious diseases by contributing to analytical chemistry activities for small molecule programsin early development (preclinical throughPhase 1). Responsibilities include analytical support of process and formulation development activities,characterization and stabilityof drug substance and drug products, as well as contributing scientifically to the resolution of broader drug development challenges in collaboration with other R&D functions. The ideal candidate will have knowledge of laboratory techniques commonly used in the analysis of pharmaceuticals such as LC, GC, and KF.

Key Duties and Responsibilities:

• Designs, executes, and interprets experiments, with a high degree of reliability and independence.Compiles results into conclusions or recommendations for discussions with manager

• Performs method developmentexperiments (LC, GC, KF) in collaboration with Subject Matter Expert (SME) teams

• Designed and executes phaseappropriate stabilitystudiesfor drug substance and drug products

• Maintainsaccuratelaboratory notebooks

• Presents results at internal Project Team research meetings

• Performs experimental troubleshooting

• Contributes collaboratively to team goals

Knowledge/Skills:

• The ability to work successfully in a team/matrix environment

• The ability to work in a fast-paced environment, manage priorities, andmaintaintimelines for multiple projects

• Proven technical prociency anddemonstratedskill in designing,executingand interpreting experiments.Usesown judgment to execute follow-up experiments, including troubleshooting

• Understanding ofLC, KF, GC, and other techniques commonly used for pharmaceutical analysisand how they are applied. Fundamental understanding of method development and validationof these techniques

• Demonstrates understanding of own discipline and aspects of drug development regulations and compliance

• Demonstrates ability to provide high quality data collected in a compliant fashion in support of regulatory submissions and/or manufacturing

• Demonstrates effective, self-sufficient communication skills, especially in peer/team discussions

• Good written and verbal communication skills

Education and Experience:

• Bachelor's degree (or equivalent degree) and 4+ years of experience in analytical development program or other analytical support function, or

• Master's degree (or equivalent degree) and 0-2 years of experience in analytical development program or other analytical support function

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com