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Disease Area Head (DAH) - GI/GU Oncology

Genentech
United States, California, South San Francisco
Nov 25, 2025
The Position

Our Global Pharma Strategy (GPS) team plays a pivotal role in shaping the future of healthcare by driving the strategic direction of our innovative product portfolio. As a member of the GPS team, you will be at the forefront of transforming groundbreaking scientific discoveries into accessible and impactful healthcare solutions for patients worldwide. We are seeking a dynamic and visionary professional who thrives in a collaborative environment and is passionate about making a difference.

As the Disease Area Head for GI and GU Cancers, you lead large-scale, multidisciplinary teams throughout the R&D path to value, composed of direct and indirect reports, with considerable influence on the company's strategic, financial and operational performance. You will lead a team of senior leaders who are accountable for high quality strategic guidance for early pipeline decision making and leading lifecycle management in late stage; providing global, cross-functional leadership for research & development, technical, and commercialization activities for molecules/products across the GI and GU Cancer Disease Area.You are a standing member of the Oncology Therapeutic Area (TA) Leadership Team and make significant contributions to the long-range vision, strategy and plans for the TA and Roche Pharma overall. You will also be a standing member or co-lead various global governance committees, such as Business Boards and Development Boards.

In this position, your responsibilities include:

  • Lead large-scale multidisciplinary teams, composed of direct and indirect reports, with considerable influence on the Disease Area's (DA) overall ambition and strategic, financial and operational performance.

  • In collaboration with your team and cross-functional partners, you will make significant contributions to the 2030 Pharma vision as you shape the end-to-end Disease Area Strategies and plans.

  • In partnership with the Research and Development organizations (Reds, PD), Business Development, Commercial Leadership Teams and Global Medical Affairs (PDMA), you and your team will shape the future portfolio for the DA and will lead global lifecycle management and development of all solutions (molecules/products) within the Disease Areas.

  • You will have global responsibility for multiple molecules/products, which can include multiple line extensions. You will oversee a team of senior leaders who are accountable for coordinating and managing the lifecycle of late-stage and on-market products; providing global, cross-functional leadership for all Research & development, technical, manufacturing, and commercial activities.

  • Co-leading the Breast Cancer Disease Area Team that develops and implements long-term end-to-end Roche strategy in the assigned Disease Areas.

  • In partnership with the functions mentioned above, leading development and execution of a robust, integrated and cohesive end-to-end vision and strategy for the overall franchise, which includes individual global lifecycle strategies and plans for all products/indications across the assigned franchise.

  • Developing and managing the Breast Cancer Disease Area budget to ensure financial targets are met and to optimize resource allocation

  • Contribute to shape the external Disease Area ecosystem, engaging with the world's most renowned Therapeutic Area Experts, Patients' Advisory Groups, Healthcare industry leaders, Biotech.

Who you are:

  • Extensive experience in the pharmaceutical/biotechnology industry, with development and therapeutic area experience in the relevant Disease Area.

  • Outstanding people leader and developer in a multicultural environment and virtual set-up, with demonstrated ability to lead business and people through high impact change and transformation.

  • Experience leading large cross-functional organizations, preferably in the domains of drugs research and development, drugs and indications pre-launch and launch, throughout the entire cycle of strategy setting and execution.

  • Deep understanding and knowledge of the Disease Area competitive landscape, and experience in partnering with business development/acquisitions teams.

  • Outstanding partnership skills: with a track record that includes finding opportunities that have improved results in areas beyond direct management or influence.

  • Confirmed abilities to work effectively in multicultural, matrix environments, across numerous time zones.

Additional Requirements:

  • Education: Master's degree. MD, PhD or MBA are strongly preferred.

  • Required to travel globally approx 30% of the time.

  • Working language: English.

Location: South San Francisco (primary) or Basel, Switzerland (secondary). Relocation benefits are available for this position.

The expected salary range for this position based on the primary location in South San Francisco is 350,030-430,390. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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