New

Senior Statistical Programmer II

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Dec 09, 2025
Job Description Employer: Vertex Pharmaceuticals Incorporated JOB TITLE: Senior Statistical Programmer II LOCATION: 50 Northern Ave., Boston, Massachusetts, 02110 OPENINGS: 1 DUTIES: Codes complex SAS programs (including Macro language, SAS/STAT and SAS/GRAPH) for applications designed to analyze and report complex clinical trial data and for electronic review, exchange, transformation, and submission of data in CDlSC SDTM format; consistently meeting objectives of the study. Performs quality control checks of SAS code and output produced by other Statistical Programmers. Demonstrates proficient knowledge of clinical development and medical data. Solves clinical trial reporting problems and has a proven technical proficiency in supporting daily operations and ensuring that project tasks are completed accurately with limited supervision. Creates CDISC data sets by transforming various raw data sources, including different Electronic Data Capture (EDC) databases and Interactive Web Response Systems (IWRS), tables, figures, and listings reporting and submitting the results of clinical trials for investigational medications. Works with all types of coding dictionaries (MedDRA and WHODD) commonly used by the pharmaceutical industry. Works in a team environment providing technical leadership and solving clinical trial reporting problems within budget and customary time line constraints while assuring high quality standards. Telecommuting permitted. REQUIREMENTS: Employer will accept a Bachelor's degree, or foreign equivalent, in Computer Science, Biostatistics, Statistics, Data Science, Engineering, Biology, Pharmacy or a related field and 5 years of experience in the job offered or in a Senior Statistical Programmer II-related occupation. Alternatively, employer will accept a Master's degree, or foreign equivalent, in Computer Science, Biostatistics, Statistics, Data Science, Engineering, Biology, Pharmacy or a related field and 2 years of experience in the job offered or in a Senior Statistical Programmer II-related occupation. Position requires demonstrable experience in the following: Writing SAS programs using SAS/BASE, SAS/MACRO, SAS/GRAPH, SAS/STAT, and SAS/SQL to map raw clinical data to CDISC compliant datasets and create tables, figures, and listings reporting results of clinical trials for investigational medications; Knowledge on Metadata Submission Guidelines (MSG V2.0) and annotate CRF with SDTM variables; Knowledge on generation of define.xml 2.1; Perform quality control on vendor deliverables; Review CRF design specifications, edit check specifications, manual data review specifications, and vendor data transfer specifications as study statistical programmer; Knowledge on Clinical Study Data Reviewer's Guide (cSDRG) and Analysis Data Reviewer's Guide (ADRG) documents; and Reviewing Statistical Analysis Plan. Rate of Pay: $124600.00 - $186900.00 CONTACT: Send Resume to futuretalent@vrtx.com. Reference 12140.759. EOE. #LI-DNI Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com