New

Senior Technician - Hematology & Oncology

Columbia University
United States, New York, New York
Jan 14, 2026
Job Type: Support Staff - Union Bargaining Unit: SSA Regular/Temporary: Regular Hours Per Week: 35 Salary Range: $61,692.40 - $61,692.40 The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. Position Summary We are seeking a highly motivated candidate for a full-time Senior Research Technician position at Columbia University Irving Medical Center in the Ben Izar Laboratory. Our research focuses on the interactions between immunity and cancer evolution, metastasis, and drug resistance. The lab employs cutting-edge technologies, including single-cell genomics, integrated CRISPR screens with single-cell readouts, and highly multiplexed imaging. We work with patient-derived cancer tissue, cell line models, and mouse models of cancer biology and immunotherapy, while continuing to develop novel technologies. Our ultimate goal is to improve the lives of cancer patients through innovation. The successful candidate will work closely with Dr. Izar to maintain an efficient laboratory environment, conduct experiments, collaborate with other lab members, and engage with research teams across the Columbia Center for Translational Immunology (CCTI) and the broader Columbia University Medical Center community. Candidates are not expected to have prior experience in all listed techniques; however, competitive applicants will demonstrate eagerness to learn, flexibility, strong organizational skills, and excellent communication and record-keeping abilities. Responsibilities Set up, calibrate, maintain, and troubleshoot laboratory equipment. Process tissue samples from preclinical animal models and patients, including cryopreservation, cell fractionation (FACS/MACS), and extraction of nucleic acids and proteins. Prepare and maintain basic dry and wet chemicals and other common laboratory reagents. Perform conventional PCR and quantitative RT-PCR. Conduct immunoblotting and related assays. Maintain cell lines and primary cells in tissue culture. Execute in vitro therapeutic studies, including proliferation and metabolic luminescence assays. Perform fluorescence- and magnetic-activated cell sorting (FACS and MACS). Generate high-throughput single-cell sequencing libraries from DNA and RNA specimens. Manage mouse colonies. Conduct high-content imaging and multiplexed immunofluorescence imaging using specialized equipment. Maintain detailed records of laboratory work and communicate results via shared electronic platforms. Share responsibility for operation and maintenance of common laboratory equipment. Order reagents and supplies based on lab needs and member requests. Assign routine lab tasks and equipment maintenance responsibilities to team members. Monitor compliance with Environmental Health and Safety standards and lab-specific SOPs. Participate in regular meetings with Dr. Izar and the grants management office to review lab operations. Perform additional related duties as assigned. Minimum Qualifications Bachelor's degree and at least one and one-half years of related experience or equivalent in education, training and experience. Strong communication skills, including timely responses during business hours. Preferred Qualifications Experience in microscopy, genomics, and computational analyses is preferred but not required if willing to learn. Other Requirements The candidate selected for this position is required to undergo a drug screening test prior to a final offer of employment being made Participation in the medical surveillance program Work with laboratory animals Potential bloodborne pathogen exposure Successful completion of applicable compliance and systems training requirements Equal Opportunity Employer / Disability / Veteran Columbia University is committed to the hiring of qualified local residents.