RESEARCH SCIENTIST - SENIOR HR (PHARMACOLOGY)

ABOUT US:

Calibr-Skaggs Institute for Innovative Medicines was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities. Calibr-Skaggs is a division of Scripps Research, a first-of-its-kind, nonprofit translational research institute dedicated to creating the next generation of medicines. Scripps Research is ranked the most influential institution in the world for its impact on innovation. Our educational and training programs mold talented and committed students and postdocs into leading-edge scientists. Leveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. We expand basic knowledge in the biosciences and use these fundamental advancements to develop profound innovations that improve wellbeing. Calibr-Skaggs' drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases. If you have a passion for making a difference, this could be your opportunity to join our transformative team.

POSITION TITLE:Senior Research Scientist, In Vivo Pharmacology

POSITION SUMMARY:

Calibr is seeking a highly motivated in vivo pharmacology scientist to join the Pharmacology group and support multiple drug discovery and early development programs. The successful candidate will play a key role in the design, execution, analysis, and communication of in vivo pharmacology studies, with opportunities to contribute to in vitro assay development and sample analysis depending on experience.

Title, scope of responsibility, and level of study ownership will be determined based on qualifications, demonstrated expertise, and organizational needs.

ESSENTIAL DUTIES & RESPONSIBILIES:

Provide in vivo pharmacology support for multiple drug discovery and early development programs across a range of therapeutic areas.

• Design, execute, and analyze in vivo proof-of-concept, efficacy, and mechanistic studies in close partnership with project teams
• Independently lead assigned studies, including experimental planning, execution, troubleshooting, data analysis, and reporting, while ensuring scientific rigor and data quality
• Contribute to the development, adaptation, and application of disease-relevant animal models.
• Maintain accurate, detailed experimental records in compliance with institutional policies, IACUC requirements, and applicable regulations.
• Collaborate closely with principal investigators, project leads, and cross-functional partners to interpret data and support program decisions.
• Support animal ethics and compliance activities, including contributing to IACUC protocol development, amendments, and reviews, as appropriate.
• Perform related duties incidental to the work described herein, including operational support of vivarium-based studies as needed.

QUALIFICATIONS REQUIRED:

• Bachelor's or Master's degree in a biology-related field.
• 10+ years of hands-on experience conducting in vivo pharmacology or physiology studies in an academic or industry environment.
• Familiarity with federal, state, and/or industry standard operating procedures and regulations related to animal welfare and in vivo research.
• Strong attention to detail and commitment to high-quality data generation and documentation.
• Excellent oral and written communication skills.
• Ability to manage multiple studies and projects in parallel.
• Ability to work independently, with level of supervision and study ownership appropriate to experience.
• Proficiency with standard productivity tools (e.g., Microsoft Office)
• Willingness to occasionally work off-hours, weekends, or holidays as study needs require.

PHYSICAL REQUIREMENTS:

This position works in a laboratory environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

COMPENSATION:

The expected hiring range for this position is $95,000 to $125,000 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements.

COMPREHENSIVE BENEFITS INCLUDE:

• Employer Contributed Retirement Plan - Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) using your own pre or post-tax dollars.
• Full suite of Health and Welfare plans including four medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Access to Flexible Spending Accounts (Medical/Dependent Care).
• Competitive vacation and sick leave policies.
• Free, on-site parking.

The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff.

EEO Statement:
The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture, and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.