New

Manager, Medical Strategy Operations

Apellis Pharmaceuticals, Inc.
life insurance, flex time, 401(k)
United States, Massachusetts, Waltham
Feb 18, 2026
Opportunity awaits those up to the challenge of developing transformative therapies across a broad range of debilitating diseases. Summary: The Manager, Medical Strategy Operations, is part of a highly matrixed team supporting the Medical Affairs organization. This role delivers operational support such as operational planning and tracking, process improvement activities, and contracting and purchase orders for HCP and vendor engagements. In addition to delivering operational support such as planning and tracking, process improvement activities, and contracting and purchase order management for HCP and vendor engagements, this role exercises independent judgment and discretion to identify risks, resolve operational challenges, and implement scalable solutions that enhance efficiency and compliance across therapeutic areas. This role ensures compliance, operational efficiency, and seamless execution of Medical Affairs activities while serving as a strategic operational partner to Medical Affairs leadership. Roles and Responsibilities: Medical Affairs Operational Support Build strong relationships with Medical Affairs leadership, Field Medical, Legal, Finance and Procurement, and external partners to drive execution excellence Serve as an operational advisor to Medical Affairs leadership, proactively identifying execution risks and recommending mitigation strategies Lead the operational planning process for Medical Affairs initiatives, including timeline development, resource coordination, and tracking of key milestones Collaborate cross-functionally to identify opportunities to streamline Medical Affairs processes and implement best practices Systems and Process Management Contracting Serve as Medical Affairs lead and subject matter expert in the Agiloft contract management system Own end-to-end contract lifecycle strategy for Medical Affairs engagements, including vendors, HCPs, and consultants Partner with Legal to ensure timely and compliant contract execution Monitor contract lifecycle and maintain documentation to ensure audit readiness and alignment with internal controls Financial Operations Serve as Medical Affairs lead and subject matter expert in the SAP financial system Partner with Finance to support annual budget planning, forecasting, and accrual management for Medical Affairs activities Create and track requisitions, purchase orders (POs), vendor invoicing, and monthly accruals in partnership with Finance and Procurement Education & Experience Bachelor's degree required Minimum of 4 years of experience in pharmaceutical/biotechnology including 2 years in a Medical Affairs or Operations related role Experience managing contracts, purchase orders, and vendor invoicing, familiarity with SAP preferred Knowledge, Skills & Abilities Demonstrable project management skills; proven ability to manage multiple tasks to conclusion, within allotted timelines/deadlines, and without compromise to quality of work output Demonstrated ability to exercise sound judgment, prioritize competing demands, and make operational decisions with limited oversight Strong understanding of Medical Affairs operations, compliance requirements, and cross-functional collaboration Demonstrated aptitude to learn new skills, systems, and software Travel Requirements: Education: Pay Information: Work Arrangement: Benefits and Perks: Apellis offers a comprehensive benefits package, including a 401(k) plan with company match, inclusive family building benefits, flexible time off, summer and winter shutdowns, paid family leave, disability and life insurance, and more! Visit https://apellis.com/careers/benefits/ to learn more. Company Background: Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company leading the way in complement science to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two C3-targeting medicines approved to treat four serious diseases. Breakthroughs for patients include the first-ever therapy for geographic atrophy, a leading cause of blindness, and the first treatment for patients 12 and older with C3G or primary IC-MPGN, two severe, rare kidney diseases. We believe we have only begun to unlock the potential of targeting C3 across many serious diseases. For more information, please visit http://apellis.comor follow us on LinkedIn andX. EEO Statement: Apellis is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Apellis strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS/HIV status, smoker/nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law. For San Francisco postings: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Other Duties: Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.