Research Pro 3

About the Position
The Department of Lab Medicine and Pathology, at the University of Minnesota invites applications for a full-time Researcher 3 position to support human gene replacement mouse modeling research for Parkinson's disease, Alzheimer's disease and Alzheimer's disease related dementias. The successful candidate will assist with reproductive technology procedures in mice for creating a variety of mouse models of human disease. A successful candidate will take a new perspective using existing solutions, work independently with minimal guidance, and will come to the position with working knowledge of the field of work.

Responsibilities:
* 35% Lead and conduct mouse embryonic stem cell culture and gene targeting.
* 20% Independently analyze and validate models with expression assays. Includes accurate record keeping of daily experiments of various ongoing projects, genotyping, assays and tests performed as demanded by the projects.
* 20% Utilize DNA cloning techniques for construct design. The employee will analyze data from these experiments, formatting the information for easy communication. Employee synthesizes data from experiments with prior knowledge and information from literature sources to explain results and propose future directions. Data and experimental details are thoroughly recorded and maintained in a lab notebook, for ease of access in manuscript preparation and by other lab members. Results are communicated in regular lab meetings and one-on-one supervisor meetings. Written descriptions of experimental details and results are provided for regulatory documents, manuscripts, and grant preparation when needed.
* 15% Assist with generating chimeric mice from targeted mES cell by injection into blastocysts.
* 5% Train undergraduate and master's students, and rotating/new graduate students. The
employee will introduce new students to typical laboratory techniques and help formulate
action plans for said students to independently complete projects after training. The
Researcher 3 position will act as a repository of institutional laboratory knowledge and a
source of technical information for co-workers.
* 2.5% Maintain a clean and orderly work environment.
* 2.5% Follow established biological, chemical, and physical safety procedures

All required qualifications must be documented on application materials.
Qualifications
Required Qualifications
* BS/BA in Molecular Biology, Biology or related field and four years of related experience or a combination of education and experience to equal eight years
* Aseptic techniques and cell culture experience.
* Experience in mouse handling and willingness to learn assisted reproductive techniques.
* Hands-on experience with molecular biology procedures (DNA, RNA and Protein isolation, PCR, gel electrophoresis, Westerns)
* Ability to work well within the lab group and with collaborators.

Preferred Qualifications
* Mouse Embryonic Stem Cell (mESC) culture experience.
* Experience with various assisted reproductive techniques in the mouse to include
superovulation, IVF, preparing pseudo pregnant recipients, surgical transfer of embryos and
sperm cryopreservation.
* DNA cloning experience.
* Excellent organizational and oral/written communication skills
* Excellent problem solving skills

Pay Range: $31.72 - 37.67/hr; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type: Civil-Service & Non-Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).