|
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to
transform the lives of patients and their families. We are dedicated to developing
life-changing medicines for people with serious diseases - often with limited or no
therapeutic options. We have a diverse portfolio of marketed medicines, including leading
therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments.
Our patient-focused and science-driven approach powers pioneering research and development
advancements across our robust pipeline of innovative therapeutics in oncology and
neuroscience. Jazz is headquartered in Dublin, Ireland with research and development
laboratories, manufacturing facilities and employees in multiple countries committed to
serving patients worldwide. Please visit
www.jazzpharmaceuticals.com
for more information.
The Executive Medical Director, Oncology Clinical Development, and Head of Early Oncology Programs is a senior R&D leader responsible for driving the strategy, design, and execution of earlystage oncology clinical programs (Phase 0-2). This role oversees a portfolio of innovative therapeutic candidates and plays a critical role in shaping the early development pipeline, integrating translational science, biomarker strategy, and clinical execution to advance assets efficiently to proofofconcept and latestage development. The leader partners crossfunctionally with Discovery, Translational Medicine,
Regulatory, Biostatistics, Clinical Operations, Safety, and Commercial to ensure
highquality decisionmaking and timely progression of programs. Essential Functions/Responsibilities
* Define the scientific and clinical development strategy for the early oncology portfolio across multiple modalities and tumor types. Lead the design of firstinhuman (FIH), doseescalation, doseexpansion, and other earlyphase clinical trials to establish safety, PK/PD, and preliminary efficacy.
* Serve as the senior clinical voice for early oncology, influencing portfolio decisions, go/nogo criteria, and prioritization across programs.
* Drive integration of translational and biomarker strategies to enhance patient selection and accelerate proofofmechanism/proofofconcept. Clinical Development & Execution
* Oversee medical monitoring and clinical deliverables for earlyphase oncology
studies.
* Provide expert clinical input into protocol development, IND submissions, regulatory interactions, and clinical study reports.
* Ensure early clinical programs meet the highest standards of scientific rigor, patient safety, and compliance with global regulations.
* Review and interpret emerging clinical and translational data, informing dose
selection, cohort expansion, and program advancement. CrossFunctional & External Collaboration
* Partner with Discovery and Translational teams to shape early pipeline strategy and mechanismofaction understanding.
* Collaborate closely with Clinical Operations, Biostatistics, and Regulatory Affairs to enable efficient study startup, enrollment, and execution.
* Represent the company in external interactions, including KOL engagements,
academic collaborations, scientific advisory boards, and regulatory meetings (FDA, EMA, etc.).
* Provide clinical leadership for alliance partners and codevelopment collaborations. People Leadership
* Lead and mentor a team of medical directors, clinicians, and clinical scientists working across early oncology programs.
* Develop organizational capability in early development strategy, medical excellence, and decisionmaking.
* Foster a culture of scientific curiosity, accountability, collaboration, and operational excellence.
Required Knowledge, Skills, and Abilities
* MD or MD/PhD required; board certification in Oncology or Hematology/Oncology.
* 10+ years of industry experience in oncology drug development, including significant leadership in earlyphase clinical development.
* Proven success advancing oncology assets from IND through Phase 1-2, including firstinhuman studies.
* Experience interacting with global regulatory agencies on earlyphase clinical
programs.
* Deep understanding of tumor biology, translational science, PK/PD principles, and innovative clinical trial design.
* Demonstrated ability to lead clinical strategy for multiple programs simultaneously.
* Strong analytical skills and ability to interpret complex clinical and biomarker data.
* Exceptional communication skills and executive presence; capable of influencing across multiple organizational levels.
* Experience managing and developing highperforming clinical teams. Required/Preferred Education and Licenses
* Medical degree, MD (MD/PhD preferred) with specialized training in Hematology, Oncology;
U.S. Board Certification/Eligibility preferred Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $348,000.00 - $522,000.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html.
|
Jazz Pharmaceuticals
$348,000.00 - $522,000.00
vision insurance, 401(k)
Mar 03, 2026