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It's More Than a Career, It's a Mission. Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day. Our Mission People who live with cancer - those who work to prevent it, fight it, and survive it - are at the heart of every decision we make. Bringing the most innovative medical minds together with the most passionate caregivers in their communities, we are transforming care and personalizing treatment. Through clinical excellence and cutting-edge research, SCRI is redefining cancer care around the world. The Lead Intelligent Solutions Engineer is a senior, handson technical builderleader accountable for delivering AI and intelligent automation solutions endtoend, from problem framing through production deployment and sustained value realization. This role personally designs, builds, and scales LLM and agentbased automations while owning solution architecture, technical quality, delivery outcomes, and enterprise standards. This position requires deep technical expertise, strong architectural judgment, and the ability to independently drive complex, ambiguous initiatives to completion. The role is not oversightonly; it is focused on custom AI development, intelligent automation, and solution execution using large language models, agents, orchestration frameworks, and enterprise integrations. In addition, this role is expected to evangelize and engage the business, translating opportunities and problems into tangible, trusted, productionready AI solutions that measurably improve productivity, quality, cycle time, and decisionmaking across SCRI. Duties include but are not limited to: HandsOn AI & Intelligent Automation Development (Primary Accountability)
Independently design, build, and maintain:
AI prompts and prompt libraries LLM based agents and copilots Chatbots, automation scripts, and end to end intelligent workflows Lead rapid prototyping and experimentation; convert successful pilots into scalable, production grade solutions Own the day-to-day technical health of deployed solutions, including monitoring, troubleshooting, performance tuning, and reliability improvements Build and maintain robust integrations with enterprise platforms using APIs, services, data pipelines, and workflow orchestration tools
End to End Solution Architecture & Delivery Ownership
Serve as the end-to-end AI solution architect for assigned initiatives, making architectural decisions and implementing them hands on Define and standardize solution patterns for:
Agent architectures (RAG, tool calling, multi agent orchestration) Integration and data flow design Environmental promotion and deployment strategies (dev/test/prod) Own delivery planning with clearly defined value metrics, success criteria, and timelines Proactively identify technical risks, trade offs, and dependencies and drive resolution
Use Case Execution & Enterprise Impact
Lead execution for highimpact, enterpriselevel AI and automation use cases, particularly complex or manual processes with measurable value potential Translate loosely defined business problems into durable, productionready AI solutions Typical use cases include, but are not limited to:
LLMbased agents for case intake, triage, summarization, and decision support Intelligent document processing across emails, PDFs, forms, and unstructured content Workflow automation for finance, operations, compliance, research, or shared services Embedded AI assistants integrated into enterprise systems to reduce manual effort, errors, and cycle time Partner closely with business owners to validate outputs, refine logic, and ensure solutions are adopted, trusted, and operationalized
Governance, Security & Compliance (Lead Level Accountability)
Ensure all solutions comply with enterprise AI governance standards, ethical AI principles, and corporate policies Design and implement securebydefault solutions, including documentation, traceability, monitoring, and audit readiness Anticipate and mitigate risks related to data privacy, access control, model behavior, hallucinations, bias, and operational resilience Partner with architecture, security, and data governance teams to ensure compliant solution design, especially within regulated environments
Evangelism, Enablement & Technical Leadership
Evangelize AI and intelligent automation capabilities across the organization by:
Engaging business stakeholders Translating opportunities into concrete solution concepts Demonstrating value through working solutions Produce highquality technical documentation, user guides, and SOPs Lead handson enablement sessions, workshops, and knowledge transfer to drive adoption Act as a technical mentor and thought leader, influencing standards, patterns, and best practices across AI and automation initiatives Collaborate with business and technology partners to continuously improve AIenhanced workflows
Mandatory: The following are mandatory expectations of all SCRI employees.
Minimum Qualifications:
Knowledge: A body of information needed to perform tasks; May be obtained through education, training or experience.
Advanced knowledge of generative AI, machine learning, NLP, agentic frameworks, and AI solution architectures Strong understanding of AI governance, MLOps, and enterprise risk management Healthcare, life sciences, or clinical research technology domain knowledge.
Skills: The proficiency to perform a certain task.
Proven experience delivering complex, productiongrade AI and automation solutions as a handson builder Deep proficiency in prompt engineering and applying Generative AI to enterprise workflows Strong programming skills (typically Python and/or JavaScript) with experience in APIs, data transformation, version control, and deployment practices Demonstrated experience building agentic AI solutions, including RAG architectures, orchestration frameworks, and toolcalling patterns Experience with Microsoft AI ecosystem tools (e.g., Copilot Studio, Power Platform, Azure AI / Azure OpenAI) strongly preferred Ability to rapidly prototype while maintaining enterprisegrade security, reliability, and governance Demonstrated ability to operate as a senior, endtoend AI solution architect while remaining handson Comfortable owning ambiguous, highvisibility initiatives with minimal direction Strong stakeholder influence skills; able to align technical decisions with business outcomes in a matrixed environment Track record of translating concepts into shipped, adopted, enterprise solutions
Abilities: An underlying, enduring trait useful for performing duties.
Ability to operate simultaneously at strategic, architectural, and engineering levels. Ability to influence change and drive adoption across teams. Ability to prioritize, execute, and deliver outcomes under evolving requirements.
Preferred Qualifications:
Healthcare, life sciences, or clinical research domain experience Experience delivering solutions in regulated, compliancedriven environments
Interested candidates should submit their application through https://www.scri.com/careers/. Applications will be accepted through April 9, 2026. Please ensure all required materials are included as outlined in the posting.
About Sarah Cannon Research Institute Sarah Cannon Research Institute (SCRI) is one of the world's leading oncology research organizations conducting community-based clinical trials. Focused on advancing therapies for patients over the last three decades, SCRI is a leader in drug development. In 2022, SCRI formed a joint venture with former US Oncology Research to expand clinical trial access across the country. It has conducted more than 750 first-in-human clinical trials since its inception and contributed to pivotal research that has led to the majority of new cancer therapies approved by the FDA today. SCRI's research network brings together more than 1,300 physicians who are actively enrolling patients into clinical trials at more than 250 locations in 24 states across the U.S. Please click here to learn more about our research offerings.
We care about the well-being of the patients and communities we serve, and that starts with caring for our people. That's why we have a Total Rewards package that includes comprehensive benefits to support physical, mental, and financial well-being. Our Total Rewards offerings serve the different needs of our diverse colleague population and ensure they are the healthiest versions of themselves. For more information regarding benefits through our parent company, McKesson, please click here.
As part of Total Rewards, we are proud to offer a competitive compensation package. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application. McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates. McKesson job postings are posted on our career site: careers.mckesson.com. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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McKesson Corporation
Mar 31, 2026