Post-Doctoral Fellow

Job Summary:

This position is involved in studies aimed at understanding the role of transcriptional gene regulation in hematopoietic stem cells and mutations found in pediatric bone marrow failure. Specifically, the Fellow will help investigate the role of Taspase1 mutations in early hematopoietic failure. The Fellow is expected to conduct research projects, to think independently, be highly motivated, design and carry out experiments, analyze data, and interpret and publish results. It is the Fellow's responsibility to fully understand the technical details of Dr. Foresters' projects as well as how each applies within the larger context of defining novel therapeutic agents in Hematological Research and broadening our understanding of mechanisms underpinning pediatric marrow failure.

Key Responsibilities:

* Mechanism based discovery of aberrant transcription in pluripotent tissues.

* Characterization of hematopoietic differentiation from iPSCs.

* Use of animal model systems to study hematopoietic engraftment.

* Engage in self-directed work with bioinformatic core to develop expertise in analysis of nascent transcription, CUT&Run and protoeomics (if not already proficient)

* Analysis and Publication of Research Data (20% of Time Spent)

* Mentoring of students and technical staff (5% of Time Spent)

* Prepare data and manuscripts for publication

* Prepare grant proposals to obtain independent post-doctoral funding

* Actively participate in and present data at group meetings, journal clubs and conferences

* Work in conjunction with the PI and other lab staff to achieve programmatic goals, including student supervision

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, Colorado.

Why Join Us:

Why work for the University?

The University of Colorado offers a comprehensive benefits package. To see what benefits are available for Post-Doctoral Fellows, please visit:

Payroll & Benefits Orientation for Post-Doctoral Fellows | University of Colorado (cu.edu)

benefits guide cover-post-doc-2024 (cu.edu)

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

• Doctor in Philosophy (PhD) in Cancer biology/molecular biology/biochemistry or related field.

• Minimum of 2 years of cellular or molecular immunology experience

• Experience with flow cytometry

Condition of Employment:

• Must be willing and able to pass a national criminal background check

Preferred Qualifications:

• Graduate training in a biomedical laboratory setting, studying immunology, molecular biology, hematology and/or stem cell biology.

• Experience with the use of advanced flow cytometry equipment (including LSRII, Sony XDP Sorter, Cytek Aurora and FACSAria II) for analysis and sorting of cells, and development of multicolor antibody staining panels.

• Experience in mouse handling, husbandry and dissection.

• Experience in experimental hematology and molecular biology assays and techniques, including HSC isolation and analysis, and high-throughput sequencing.

• Experience in bioinformatic analysis of large datasets with proficiency in R or Python

• Candidates that have successfully obtained competitive, extramural funding during their doctoral studies are preferred.

Knowledge, Skills and Abilities:

• Excellent written and verbal communication skills.

• Ability to work independently and as a team member within a research environment.

• Ability to work efficiently and effectively with computer software including Microsoft Office.

• Skilled with the use of aseptic mammalian cell culture techniques.

• Skilled with common laboratory techniques and equipment consistent with PhD-level graduate training.

• Ability to commit to an independent scientific career in stem cell biology, immunology, or a related field, with a proven high degree of independence and self-motivation to achieve these ends.

• Ability to work a flexible schedule based on the needs of the project.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Paul Lopez paul.j.lopez@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until position is filled. For best consideration, apply by June 30, 2026.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

$63,480-70,500.

The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

Equal Employment Opportunity Statement:

The University of Colorado (CU) is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.