Clinical Research Coordinator - Duke Cancer Institute

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Brain Tumor Center at Duke Health is seeking a highly motivated Clinical Research Coordinator to join our dynamic and mission-driven research team. In this role, you will lead day-to-day operations across multiple clinical study teams, playing a critical part in advancing innovative research that directly impacts patient care and outcomes in neuro-oncology.

You will serve as a central leader and subject matter expert, guiding teams through complex clinical research processes-from study start-up and regulatory compliance to data integrity and study closeout. Your work will ensure that trials run efficiently, participants are engaged and retained, and research data is accurate, secure, and impactful.

On a daily basis, you will collaborate with investigators, sponsors, and cross-functional teams while mentoring staff, optimizing workflows, and implementing strategies to meet recruitment and study goals. This is an exciting opportunity for someone who thrives in a fast-paced, detail-oriented environment and wants to make a meaningful contribution to cutting-edge clinical research.

Minimum Requirements:

• Associate's degree required
• Minimum of two years of relevant clinical research experience
• Completion of the DOCR North Carolina state-approved Clinical Research Apprenticeship program may substitute for one year of experience
• Proficiency in Microsoft Office and web-based applications

Preferred Qualifications:

• Oncology/neuro-oncology, brain tumor, or clinical trials coordination experience
• Experience with clinical data management systems and electronic medical records (EMR, REDCap)
• Familiarity with OnCore or similar clinical trial management systems
• Knowledge of epidemiologic methods: cohort, case-control, survival analysis, bias/confounding assessment
• Proficiency in statistical programming (R, SAS) potentially including: 1) data cleaning, transformation, and validation; 2) descriptive and inferential analyses; 3) time-to-event and longitudinal modeling
• Familiarity with data integration across sources (clinical, biospecimen, imaging, genomics)
• Knowledge of biospecimen collection and processing protocols and linkage to clinical/epidemiologic datasets
• Experience with population-based datasets (e.g., cancer registries, real-world data sources)
• Experience in a patient-facing research or clinical environment
• Strong organizational skills with the ability to multitask and manage competing priorities
• Detail-oriented, self-starter with the ability to quickly learn new systems and processes

Other Requirements:

• Ability to manage and oversee multiple concurrent clinical trials and study teams
• Strong communication skills with the ability to collaborate across multidisciplinary teams
• Knowledge of regulatory requirements, IRB processes, and research compliance standards
• May involve handling human biological specimens (tumor, blood) in accordance with safety protocols

Be Bold.

Position Description:

• Lead clinical research operations across multiple study teams, including study start-up, regulatory compliance, participant recruitment, retention strategies, and study closeout activities
• Serve as a subject matter expert in research regulations, institutional policies, and study documentation; guide teams in navigating complex agreements (MTAs, CDAs, DUAs, etc.)
• Oversee data management and quality processes, including development of electronic data capture systems (EDCs), data validation, query resolution, and implementation of quality assurance protocols
• Manage and optimize study logistics, including specimen collection, processing, storage, and shipment, as well as resource allocation (staff, supplies, and equipment)
• Mentor and train study teams, improving communication, ensuring adherence to SOPs, and enhancing operational efficiency across studies

Choose Duke.

At Duke Health's Brain Tumor Center, you'll be part of a world-renowned academic medical institution dedicated to advancing discovery and improving patient outcomes through groundbreaking research. Our collaborative and innovative environment empowers you to contribute to meaningful scientific progress while growing your professional expertise.

Duke University is consistently ranked among the top institutions globally and is recognized for excellence in research, patient care, and education. You'll join a culture that values inclusion, innovation, and continuous learning.