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Postdoctoral Associate- Xiao Wang Lab

Broad Institute
paid time off, paid holidays, 401(k), retirement plan
United States, Massachusetts, Cambridge
May 26, 2026

Description & Requirements

The Xiao Wang group at the Broad Institute of MIT and Harvard is looking for an exceptional and energetic postdoctoral associate to join a rapidly growing, multidisciplinary research focused on developing and applying molecular and imaging tools (e.g. in situ RNA sequencing) to understand the complexity of the biological systems.

This postdoctoral position will provide an exciting opportunity to develop new sequencing/imaging strategies for multiscale brain mapping in a vibrant and interdisciplinary environment and collaborate with team members from diverse backgrounds (chemistry, biophysics, genomics and neuroscience). We emphasize the research training and career development for all lab members, and the candidate will have chances to interact with the research teams within Broad Institute and also the broader community in MIT, Harvard and the Harvard-affiliated hospitals across Boston.

MINIMUM QUALIFICATIONS

* 0+ years of postgraduate experience.

* PhD in physical/biological science, neuroscience, bioengineering, or related disciplines

* Hands-on experience with microscopy, molecular biology, animal models, and gene delivery vectors (e.g., AAV and lentivirus)

* Self-motivated, creative, persistent, responsible, attention to detail, good analytical and problem-solving skills, fast learner

RESPONSIBILITIES

* Fluorescence microscopy (living/preserved samples), electron microscopy (SEM/TEM), or CLEM (correlative light and electron microscopy)

* Design and generate AAV or lentivirus vector for the expression of transgenes in desired subcellular locations and desired cell populations

* Design, characterization, and engineering of RNA: e.g. in situ hybridization, microarray, gel electrophoresis, HPLC, SELEX, NGS, and single-cell RNA sequencing; RNA structure, RNA modification/editing, RNA localization, RNA-protein complexes, non-coding RNAs, synthetic RNAs, etc.

* Scientific investigation in neuroscience or other biological systems at the molecular (nucleic acids, proteins, lipids) and cellular (subcellular organelles, granules, membranes, synapses) levels

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.
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