New

Postdoctoral Associate

Duke Clinical Research Institute

300 West Morgan Street (Show on map)
May 27, 2026
School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. Be You. Matt Hilton, a premier researcher at Duke University, has a postdoctoral associate position in his lab working on an NIH funded project aimed at understanding the molecular regulation of post-traumatic osteoarthritis (PTOA)-associated joint degeneration and pain. A PhD is required Prior experience working with murine models of PTOA-associated cartilage catabolism and pain using pharmacologic treatments Onsite. The work is performed on-site or at a designated assignment location. Be Bold. In this position, you will Use (JAK inhibitors), histological (SafO/Fast Green and H&E stains), IHC or IF staining for cartilage catabolic and pain-related molecules, as well as cellular (cartilage and dorsal root ganglia explant cultures) and molecular (qPCR, RNA-seq) analyses. Generate data associated with the pharmacologic regulation of JAK signaling in PTOA-associated cartilage catabolism and pain Aid in the analysis and interpretation of that data Participate in manuscript preparations and revisions, and present data. Choose Duke. In Duke Orthopaedic Surgery, we aim to be the global standard of excellence today and develop the leaders of tomorrow in orthopaedics and rehabilitation research, education, and patient care. We: REACH OUT-to put the patient and their family at the center of all we do to provide the highest quality care STEP UP-to serve and lead our local and global communities with integrity and compassion MOVE FORWARD-to promote and develop excellence in education CLIMB HIGHER-to inspire through innovations in basic science, clinical, and translational research Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.