POSTDOCTORAL ASSOCIATE
 Duke Clinical Research Institute | |
 United States, North Carolina, Durham | |
| 300 West Morgan Street (Show on map) | |
 Jun 26, 2026 | |
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School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. Be You. Postdoctoral Associate - radiation-induced acute epithelial injury and fibrosis The Lee Lab (Department of Radiation Oncology, Duke University) is hiring a full-time Postdoctoral Associate to study normal tissue injury from ionizing radiation. Supported by NIH funding, the position focuses on acute and delayed radiation-induced intestinal injury, with emphasis on regenerative reprogramming mechanisms and stromal-epithelial interactions. The role employs a multi-modal research approach spanning genetically engineered mouse models, histopathology, mouse and human organoids, CRISPR-Cas9 gene editing, single-cell sequencing, and spatial transcriptomics. Be Bold. Qualifications: A PhD, MD, or MD/PhD in a biomedical sciences-related field is required, along with a peer-reviewed publication record. Experience in RNA sequencing data analysis is preferred. The ideal candidate is detail-oriented, organized, and thrives in a collaborative, fast-paced environment. Key Responsibilities * Design and execute in vivo and in vitro experiments to investigate molecular and cellular mechanisms of acute epithelial injury and delayed fibrosis following high-dose radiation exposure * Maintain the lab mouse colony, including breeding crosses, tail clip biopsies, weaning pups, and animal identification (tattooing, ear tagging) * Collect, analyze, and interpret experimental data; prepare clear and thorough reports * Prepare manuscripts for publication in peer-reviewed journals * Support grant and contract writing efforts * Assist in managing IACUC, IRB, and IBC protocols and maintain up-to-date lab safety SOPs * Flexibility to work weekends or alternative shifts as needed Choose Duke. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department. | |