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Position Title: Associate Scientist / Histotechnician
Work Location: Irvine, CA 92612
Assignment Duration: 8+ months (possible extension- performance based) Position Summary: We are seeking a detail-oriented and experienced histotechnician for an contract position supporting routine histology and immunohistochemistry (IHC) operations within the histology laboratory for Skincare R&D and Clinical Development. This is a hands-on, lab-based role responsible for the processing, sectioning, and staining of formalin-fixed paraffin-embedded (FFPE) tissues, as well as performing special stains, IHC assays, and associated imaging/documentation. Background & Context: The ideal candidate is comfortable working independently in a fast-paced environment, maintains rigorous attention to quality and consistency, and has solid foundational histology bench skills. Key Responsibilities:
Perform routine processing of FFPE tissue specimens, including trimming, embedding, and block preparation
Section FFPE tissue blocks using a microtome to produce high-quality, consistent slides for downstream analysis
Perform routine histology staining (e.g., H&E) and special stains (e.g., Fontana-Masson, Resorcin Fuchsin, Herovici, etc.) per established SOPs
Perform manual and/or automated immunohistochemistry (IHC) staining, including antigen retrieval, antibody optimization support, and chromogenic/fluorescent detection
Operate and maintain histology laboratory equipment (microtomes, tissue processors, embedding stations, autostainers, coverslippers)
Perform slide imaging/scanning and organize digital image files for study team review
Maintain accurate, detailed records of samples, staining runs, and quality control checks in line with lab documentation practices
Troubleshoot staining and tissue quality issues, escalating as appropriate
Ensure proper labeling, tracking, and chain-of-custody for tissue specimens and slides
Maintain lab supplies, reagents, and equipment calibration/maintenance logs
Adhere to all laboratory safety protocols, including handling of chemicals (formalin, xylene, etc.) and biohazardous materials
Support general lab organization, inventory management, and cleanliness standards
Collaborate with scientists and lab management within Skincare R&D and Clinical Development to meet study timelines and quality expectations
Qualification & Experience:
Associate's or Bachelor's degree in a relevant scientific field (e.g., Biology, Medical Laboratory Science, Histotechnology)
Minimum of 1-3 years of hands-on experience in a histology laboratory, including FFPE tissue processing, microtome sectioning, and routine/special staining
Strong attention to detail and consistency in a high-throughput lab environment
Ability to work independently with minimal supervision while following established SOPs
Good documentation and record-keeping habits
Ability to safely handle laboratory chemicals and biological specimens
HT or HTL certification (ASCP) or eligibility
Demonstrated experience performing IHC staining (manual and/or automated platforms)
Familiarity with slide imaging/digital scanning workflows
Experience with automated IHC/special stain platforms (e.g., Leica Bond, Ventana/Roche Discovery, Dako Autostainer)
Experience with whole-slide imaging/scanning systems
Prior experience in a pharmaceutical, biotech, or CRO research lab setting (as opposed to clinical diagnostics)
Familiarity with GLP or GxP laboratory documentation practices
Experience in skincare/dermatology-focused research or clinical development studies is a plus
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Spectraforce Technologies
Oct 12, 2026