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Laboratory Manager - Sabatini Lab

Howard Hughes Medical Institute (HHMI)
United States, Massachusetts, Boston
September 20, 2022
Primary Work Address: Dept. of Genetics, Boston, MA, 02115 Current HHMI Employees, click here to apply via your Workday account.

We are seeking an organized, dependable Laboratory Manager to join the lab team of Dr. Bernardo Sabatini on-site at Harvard Medical School in Boston. The Sabatini lab seeks to uncover the mechanisms of synapse and circuit plasticity that permit new behaviors to be learned and refined. They are interested in the developmental changes that occur after birth that make learning possible as well as in the circuit changes that are triggered by the process of learning. More information about the team and their research can be found by visiting

The Lab Manager will hold an integral role within the lab - directing the day-to-day operations involved in running the lab and serving as the liaison between the lab and various external partners. The successful candidate for this position is someone who is highly organized, has impeccable follow through, outstanding communication skills, and a strong growth mindset. This is an opportunity to have a tremendous impact on science in a large, internationally recognized molecular neurobiology research laboratory by ensuring a positive and encouraging work environment that fosters a strong and cohesive team. In addition to operational management, the Lab Manager may also participate in the research efforts of the laboratory and occasionally contribute to scientific manuscripts - performing these activities will be based on the chosen candidate's preferences and career aspirations.

The Lab Manager will be expected to work on-site in the lab on a day-to-day basis, but there is opportunity for some occasional remote work if desired once the chosen candidate has become acclimated to their responsibilities.

Principal Responsibilities

  • Writing animal protocols and ensuring compliance with institutional and Federal guidelines with respect to health, lab safety, and animal care regulations.

  • Providing training and supervision in these areas in the name of the principal investigator and be able to command the respect of technicians and highly scientifically trained doctoral level scientists.

  • Maintenance of lab reagents (such as plasmids and antibodies), their databases, and handling requests.

  • Maintenance of equipment, infrastructure, and space allocation.

  • Onboarding of new personnel, including ensuring their training and compliance with both Harvard and Federal guidelines.

  • Liaising with vendors, ordering of supplies, maintenance of inventories, service contracts, and repairs of equipment while maintaining attention to the sources and uses of grant funds for these needs.

  • Initiation and management of orders using B2P and other methods and tracking supplies and expenditures on a daily/weekly/monthly basis.

  • Potential to handle financial activities such as monitoring budgets and communicating with principal investigator about spending levels and spending patterns.

  • If desired - support lab team members with various research/experiment-related tasks.


  • A bachelor's degree in a scientific discipline is required.

  • A minimum of 3-5 years of experience working in a research laboratory, preferably in a management capacity.

  • Previous research experience in molecular biology and/or neurobiology.

  • Previous experience training other people on various protocols.

  • Previous experience with mouse research.

  • Sense of self-motivation, honesty, trustworthiness, and ability to work in a diverse environment with people from a wide variety of backgrounds.

  • Passion for efficiency, operational excellence, and process improvement.

  • Knowledge of standard safety regulations and appropriate laboratory practices applying to research in biology with demonstrated ability to engage others effectively in learning and applying appropriate practices.

  • Excellent problem-solving skills and high attention to detail.

  • Excellent organizational skills, oral and written communication skills, and teamwork skills.

  • Knowledge of computers and MS Office software.

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

HHMI is an Equal Opportunity Employer
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