Bioinformatics Specialist - Torii Lab

We are currently looking for a highly skilled Bioinformatics Specialist to work on computational projects for Dr. Keiko Torii's lab at the University of Texas at Austin. The Torii lab has a long-standing interest to unravel how plant stem cells function and contribute to growth and development, with specific emphasis on signal transduction pathways and underpinning genomic/epigenomic mechanisms. In addition to harnessing chemical and synthetic biology, they are designing and building synthetic signal transduction circuits to control plant growth and development suited for a changing climate. More information about the lab can be found here:

The ideal candidate will be an adaptable professional with strong technical skills and computational expertise who is excited to contribute to the research of a top-notch plant and developmental biology laboratory.

Essential Duties:

• Perform pipelines for quality control, normalization and mapping NGS reads from RNA-seq, ATAC-seq, and/or ChIP-seq experiments. Perform basic characterization of DEGs (expression dynamics), GO-category representations, and related bioinformatic analyses. Work with experimenters in the Torii Lab group to customize and modify scripts/pipelines tailored for specific experiments.

• Perform pipelines for sc-RNA-seq, sc-ATAC-seq experiments. Apply various dimensionality reduction techniques (such as UMAP), build trajectories, and visualize data.

• Perform multiple complex statistical analyses of the above NGS data.

• Visualization of complex dataset using R (ggplot2) or other programming languages. Modify scripts tailored for specific experiments.

• Characterize expression dynamics of homeologs in polyploid plant species.

• Perform de novo genome sequence assembly as collaboration.

Qualifications:
Education

• A master's degree in bioinformatics, computational biology, or a related discipline is required.

Experience

• A minimum of 2+ years of related research experience in computational biology and bioinformatics is required.

• Experience with R or similar programming language is required.

• Experience with NGS analysis is required.

Skills and Abilities

• Technical proficiency in current principles of database management and computational analysis, with ability to apply independent judgment to resolve problems and meet challenges.

• In-depth knowledge of specific areas of computational analysis and of general underlying principles and concepts.

• Ability to develop innovative processes to achieve goals.

• Ability to initiate and compose communications for various purposes in an appropriate style.

• Ability to review goals and determine which techniques and/or systems are required to meet them. Able to bring desired new database management and analytical capabilities to the lab with minimal supervision.

• Ability to communicate with experimental biologists.

• Ability to work inclusively and collaboratively with a diverse population.

• Ability to work well both independently and as part of a team.

• Ability to remain technologically current within the scope of the role.

• Strong written and verbal communication skills.

• Strong organizational, time management, and prioritization skills.

• Strong attention to detail with a high degree of accuracy.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

Compensation Range

Pay Type:

HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.