Senior Scientist Biomarker Science

Senior Scientist Biomarker Science

South San Francisco, CA /

Biomarker Science & Operations /

Full-time

At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration and cancer . Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

We are seeking a highly motivated individual to join the biomarker sciences team as a Senior Scientist at our South San Francisco campus. The biomarker sciences team is focused on translating novel immune targets into successful therapeutics in neurodegenerative and oncology therapeutic areas. We support clinical development by developing the biomarker strategy and providing biomarker data to inform drug dosing, guide indication/patient selection, and facilitate decision making in clinical development.

As a Senior Scientist, you will act as a biomarker lead for our preclinical and clinical programs ranging from early proof-of-concept through Phase III. To achieve this, you'll be part of a dynamic team and work closely with colleagues in Research, Development, Non-clinical, Clinical, Bioinformatics, and Regulatory Affairs to advance our drug discovery programs. Key aspects for this position will be the analysis of large datasets, a deep understanding of the drug's mechanism of action as well as of the disease biology, and experience integrating biomarkers into clinical trials to enable decision making. We are currently looking for motivated, experienced, and enthusiastic researchers to be influential in championing and developing Alector's culture of thinking independently and working collaboratively.

During your first year you will:

• Develop, coordinate, and execute our biomarker strategies for our preclinical and clinical molecules
• Serve as the Biomarker Lead in a cross-functional team to implement impactful biomarkers into our projects and perform data analysis
• Collaborate closely with research teams on the discovery of novel neuroscience biomarkers
• Manage data workstream, deliverables, timelines, and communication with internal and external partners

We'd love to hear from you if you have the following:

• Ph.D. or equivalent in Neuroscience, Immunology, or related discipline with 5-8 years of post-doctoral experience or MA/MS with 10 years relevant experience, industrial experience preferred.
• Proven experience in Alzheimer's Disease preferred
• A record of high-quality research as proven by publications in top-tier journals, external presentations, or drug development reports is required
• Analytics skills such as R, Python, or other data analysis programming
• Excellent communication and writing skills and thrive in an environment where we work independently and on cross-functional teams
• A track record of learning new skills and troubleshooting independently and take pride in being persistent, self-motivated, and efficient
• Experience in drug-development
• Great attention to detail and operational management skills
• A high level of independence and be able to develop hypotheses and direct analysis plans

#LI-BL1

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Alector is a phenomenal place to learn and grow. Alector is a dynamic environment where teams are encouraged to experiment, take ownership of decisions, and question convention to solve complex problems. At Alector, we value shared wins, perseverance, and a growth mindset.

Alector was named on Fortune's " Best Workplaces in Biopharma " top list for small and medium-sized companies for the second year! And we moved up from #16 to #11 in 2022 .

Among the things you'll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly lit offices in Oyster Point, right at the heart of Biotech Bay. Alector offers flexible remote work options, and competitive compensation and benefits. Come join us!

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other's assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation.