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Research Technician - DePace Lab

Howard Hughes Medical Institute (HHMI)
United States, Massachusetts, Boston
July 02, 2023
Primary Work Address: Dept. of Genetics, Boston, MA, 02115 Current HHMI Employees, click here to apply via your Workday account.

The DePace lab at Harvard Medical School has the long-term goal of understanding how regulatory DNA dictates transcriptional network behavior and, ultimately, organismal phenotype and evolution. Their approach is mechanistically motivated: they believe that understanding the molecular mechanisms that drive transcription will lead to models of gene regulation that canpredict the functional consequences of regulatory sequence changes and guide production ofnew types of regulatory circuits. More information about the team and their research can be found by visiting

About the Research Technician role:
As the Research Technician, you will be assisting other members in the lab with various experiments in support research goals. This position will provide you with an excellent opportunity for scientific learning, development of research skills, and direct mentorship in an intellectually stimulating environment. This would be an ideal opportunity for a hardworking, passionate, self-motivated professional who is looking for a robust 2+ year work experience with the lab before beginning graduate school, medical school, or the next step of their career path.

What we provide:

  • A competitive compensation package with comprehensive health and welfare benefits

  • The opportunity to learn new techniques and expand your knowledge and skills

  • Direct one-on-one mentorship

  • Joining the vibrant HMS systems biology community including attending seminars and building relationships with grad students and postdocs

  • Opportunities for professional and education development including academic courses

  • The potential to work on an independent project that supports the lab's larger research goals based on your capabilities

  • A team that believes in continuous learning and cultivates an environment of collaboration.

  • Strong potential for contribution to research publications

What you'll do:

  • Conduct RNA FISH experiments.

  • Use molecular biology techniques working with bacteria and DNA.

  • Learn innovative imaging methods to analyze gene expression in the Drosophila embryo using confocal microscopy.

  • Assist with the design and engineering of new Drosophila lines using CRISPR/Cas9 methods

  • Collaborate with other lab members on experimental design, creation of appropriate methods and protocols, and development of new laboratory techniques.

  • Analyze data, formulate conclusions, and create appropriate statistical presentations, including graphs and charts, and prepare and present written or oral progress reports regarding studies.

  • Actively contribute to laboratory meetings and planning sessions.

  • Other duties as assigned.

What you bring:

  • A bachelor's degree in the biological sciences is required.

  • Understanding of basic molecular biology techniques.

  • Previous hands-on research experience working in a laboratory would be a plus, but is not required.

  • Excellent verbal and written communication skills.

  • Excellent organizational, interpersonal, and time management skills with strong attention to detail.

  • Excellent analytical and problem-solving skills.

  • Proactive and self-motivated mentality with an eagerness to learn and grow.

  • Proficient computer skills with demonstrated proficiency in Microsoft Office Suite.

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

Compensation Range

$17.08 (minimum) - $21.35 (midpoint) - $27.76 (maximum)

Pay Type:

Hourly

HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.

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