Research Associate

The PIIO Immune Monitoring and Discovery Platform (IMDP) delivers cutting-edge technology to analyze the immune systems response to cancer immunotherapy. The Research Associate will play a critical role in the IMDP, focusing on the development and implementation of immune monitoring assays to support clinical and translational research. The successful candidate will work closely with a multidisciplinary team of scientists and clinicians to advance our understanding of immune responses in health and disease, particularly in the context of cancer immunotherapy.

Job Duties:

• Participate in planning, design, execution, and management of research projects in a shared resource laboratory focused on immune profiling of IO clinical trial samples, design and execute complex laboratory experiments using advanced molecular and cellular assays (spectral flow cytometry, single-cell proteomics/genomics, highly multiplexed tissue imaging, spatial transcriptomics, etc.), and collect, analyze, and interpret research data.

• Perform critical analysis of literature relevant to research being undertaken, assist in the preparation of research papers and manuscripts for publication and presentation at national and conferences and workshops, and participate in the writing of project reports, articles, and other documents.

• Oversee and coordinate periodic maintenance and testing of laboratory equipment and perform additional duties as assigned.

Minimum Qualifications:

• Bachelor's degree or equivalent experience required. Master's Degree preferred. 1-3 years of relevant experience required. 3-5 years of relevant experience preferred.

• Requires successful completion of a background check; selected candidate may be requested to completed a pre-employment physical including a drug screen.

Function: Research and Scholarship

Sub Function: Research

Band: Individualized Contributor - Specialized

Level: S1

About Us:

The PIIO is a comprehensive bench-to-bedside research initiative focused on harnessing the bodys immune system to fight cancer at all levels (https://cancer.osu.edu/piio). Launched in July 2019 as part of a $102 Million pledge from Pelotonia (pelotonia.org), the PIIO represents Ohio State's commitment to grow the exciting area of immuno-oncology. Led by founding director and renowned immunologistZihai Li, MD, PhD, the PIIO builds upon a rich portfolio of active investigator-initiated IO clinical trials being conducted at the OSUCCC James.

Research in the PIIO centers on Systems IO (a systems-wide strategy to study the anti-cancer immune response holistically to discover the next IO breakthroughs and create effective cancer immunotherapies) and Translational IO (where we turn discoveries into new or improved cancer treatments and broaden the indications and patient populations that can be treated with cellular therapy). Our Immune Monitoring and Discovery Platform (IMDP) supports each center, providing comprehensive cell-based and molecule-based immunoassay services to support basic, translational, and clinical IO studies. The PIIOs Immuno-Oncology Informatics Group (IOIG) provides data analytics for flow and mass cytometry, bulk and single-cell RNA-Seq, spatial transcriptomics and imaging, neoantigen discovery,and more.

The OSUCCC James is a National Cancer Institute (NCI)-designated comprehensive cancer center, rated Exceptional, the highest rating given to cancer centers by the NCI; is one of only a few centers funded by the NCI to conduct phase I, II and III clinical trials on novel anticancer drugs; and includes the third-largest freestanding cancer hospital in the country. Ohio Stateis located inColumbusa highly ranked, modern, affordable, friendly and diverse city. The Ohio State University is an EOE/AA/M/F/D/V employer.

Target Salary Range: $43,900 57,750