New

Regional Business Director, TTR - South Central

Alnylam Pharmaceuticals
$204,000-$276,000
paid time off
United States, Massachusetts, Cambridge
675 West Kendall Street (Show on map)
Oct 09, 2026
Overview We are looking for an experienced Regional Business Director (RBDs to support the promotion of AMVUTTRA (vutrisiran).The U.S. Food and Drug Administration (FDA) recently approved the supplemental New Drug Application (sNDA) for AMVUTTRA (vutrisiran).The approval expands the indication for AMVUTTRA, which now becomes the first and only therapeutic approved by the FDA for the treatment of ATTR-CM and the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR-PN) in adults. The RBD will be principally responsible for leading and managing a high-performing team of Business Account Executives, focusing on disease awareness and product education among healthcare professionals managing hATTR amyloidosis patients. This is an incredible opportunity to build a team and shape a market in support of patients, caregivers, and the hATTR amyloidosis community. The RBD will provide coaching to help ensure every BAE meets or exceeds target. He/she will be critical in the assessment and improvement of field and selling processes. RBDs will also need to provide insights to inform commercial strategy, given their proximity to the market, and ultimately meet and exceed performance targets. The RBD will also need to embody Alnylam values: our commitment to people, sense of purposeful urgency, passion for excellence, innovation & discovery, and open culture as well as our unwavering commitment to integrity. Additionally, an RBD will be responsible for the creation of a customer-oriented climate that focuses on an understanding of patient and customer needs, value-added services, and seamless execution. Through the building of best-in-class teams, talent development, and regular monitoring and coaching, the RBD will foster a culture of accountability. The position reports to the Executive Sales Lead role. Key Responsibilities Lead and manage a high-performing team of Business Account Executives, focusing on disease awareness, product education among healthcare professionals managing hATTR amyloidosis patients Utilize strong sales management, strategic planning skills, financial acumen, and analytical capabilities to align sales execution with overarching product strategies and market needs. Analyze market and proactively develop a forward-thinking action plan, rather than solely reacting to past events. Capable of clearly conveying the current market situation and proposed plan of action to leadership, while also ensuring the team is aligned to future objectives and expectations. Coach and develop team members to exceed performance targets, emphasizing compliance and effective local business management through strategic business planning and cross-functional alignment. Leverage proximity and familiarity of their market to provide insights that help inform the commercial strategy. Attract, manage, and retain top sales talent with a demonstrated experience in diverse specialties. Hold the team accountable to sustaining a customer-oriented culture that prioritizes understanding and meeting patient needs, delivering seamless execution and value-added services. Allocate and manage regional resources effectively that support targeted strategic and operational excellence. Align people, processes, structure, information, and communication systems within a complex ecosystem - both within and across functions. Inspire and motivate the team by clearly articulating the strategy and vision for the future. Qualifications Bachelor's degree required: science focus strongly preferred; MBA/PhD is a plus. 7+ years in sales, marketing, commercial operations, and/or account management experience in commercial healthcare organizations (i.e., Biotech, Med Device or Specialty Pharmaceuticals). 3+ years of experience in leading teams, experience building out field sales teams preferred Rare/orphan disease experience preferred. Experience training and managing BAEs to effectively promote multiple specialties. US product launch experience is helpful. In-depth reimbursement knowledge of Buy/Bill and expertise of Part B & D, working with in-house patient support services team required. Hospital / Institution knowledge and expertise with the P&T process. Deep experience in Neurology and Cardiology is preferred. Knowledge and experience with "site-of-care" development. Experience in working in various departments, managing multiple teams (sales, marketing, market access, patient services). Demonstrated leadership in working in a matrix environment and influencing management decisions. Effective planning, prioritization, management, and organizational skills. Must be familiar with relevant legal and regulatory environments in biotech/pharmaceutical industry. Significant domestic/regional travel is required (approximately 60 - 70%). Valid Driver's license required. Demonstrated commitment to ethics and integrity. #LI-EW1 #LI-Remote The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website:https://www.alnylam.com/careers U.S. Pay Range $204,000 — $276,000 USD