Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 97 |
Manager, Manufacturing Systems
Cambridge, Massachusetts
Overview The Manager, Manufacturing Systems is an integral part of the Internal Manufacturing team. This role is the end-user subject matter expert for the Manufacturing Execution System (MES) and Real-Time Modeling System (RTMS), The SME w...
1d
| Job Type | Full Time |
Senior Manager, Global Strategic Sourcing
Cambridge, Massachusetts
Role Overview The Senior Manager, Global Indirect Strategic Sourcing is responsible for leading and optimizing external spend across key G&A and Commercial category families. This role will own select subcategories within areas such as IT, ...
1d
| Job Type | Full Time |
Director, Financial Planning & Analysis
Cambridge, Massachusetts
Overview: Alnylam Pharmaceuticals is seeking a Director of Business Development FP&A to serve as a senior, finance-focused partner within the Business Development Finance organization. This role is intended for a highly analytical, enterpri...
1d
| Job Type | Full Time |
Principal Scientist, Antibody Cell Line Development
Cambridge, Massachusetts
Overview: We are seeking a Principal Scientist to join the Protein Sciences team to drive cell line and upstream process development for the production of monoclonal antibodies and antibody-oligo conjugates. The candidate will work across f...
1d
| Job Type | Full Time |
Associate Director, Clinical Pharmacology
Cambridge, Massachusetts
Associate Director, Pharmacometrics Position Summary Develop and execute population PK, PK/PD, exposure response, disease progression models, dose selection for phase 3 strategies/plans and corresponding models for the pharmacometric functi...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
Clinical Scientist Alnylam Pharmaceuticals is seeking an imaginative clinical scientist drug developer for the role of Clinical Scientist. This is an opportunity to assume a foundational and strategic role in building Alnylam's rapidly expa...
2d
| Job Type | Full Time |
Sr. Scientist, Clinical Pharmacology
Cambridge, Massachusetts
Senior Scientist - Quantitative Systems Pharmacology (QSP) Modeling Position Summary The Senior Scientist, QSP Modeling will develop and apply mechanistic quantitative systems pharmacology models to support drug discovery and development. T...
2d
| Job Type | Full Time |
Associate Director, Regulatory Affairs
Cambridge, Massachusetts
Overview The Associate Director of Regulatory Affairs Strategy will work on assigned programs with the respective Global Regulatory Portfolio Lead, Global Regulatory Lead and cross-functional team to lead and define the regulatory strategy,...
2d
| Job Type | Full Time |
Associate Scientist II, Process Sciences
Cambridge, Massachusetts
Overview: The successful candidate will be a part of the Process Chemistry group, responsible for the process development and in-house non-GMP manufacture of modified oligonucleotides and siRNAs.The successful candidate must have a strong c...
2d
| Job Type | Full Time |
Principal Associate Scientist, Process Sciences
Cambridge, Massachusetts
Overview: The successful candidate will be part of a team working on oligonucleotides manufacturing. The candidate will work closely with upstream and downstream teams in manufacturing and process development. In addition, this role will wo...
2d
| Job Type | Full Time |